ZOLEDRONIC ACID - Uses, Warnings, Side Effects, Precautions, Overdose and Brands
HUMAN PAPILLOMAVIRUS 9-VALENT VACCINE

ZOLEDRONIC ACID

Zoledronic acid is used to treat high blood calcium levels due to cancer or osteoporosis.

Suppresses osteoclast action and bone calcium discharge stimulated by tumors. It diminishes serum calcium and phosphorus, and facilitates their removal. In osteoporosis, it represses osteoclast-intervened resorption, thus decreasing bone turnover.

Zoledronic acid is used in treating the following:

  • Hypercalcemia of malignancy
  • Bone metastases associated with solid tumours
  • Osteolytic lesions associated with multiple myeloma
  • Osteoporosis in postmenopausal women
  • Increase bone mass in men with osteoporosis
  • Paget’s disease of bone
  • Prophylaxis of postmenopausal osteoporosis

Do not give Zoledronic acid to people with the following conditions:

Take extra caution in patients with the following medical conditions:

  • Patient with aspirin-sensitive asthma
  • Mild to moderate renal impairment
  • Pregnancy

Take extra caution in patients with the following medical conditions:

  • Patient with aspirin-sensitive asthma
  • Mild to moderate renal impairment
  • Pregnancy

 

Interactions

Zoledronic acid may interact with the following medicines:

  • Digoxin
  • Aminoglycosides
  • Nephrotoxic agents

Overdose & Brands

Symptoms of overdose include the following:

  • Renal impairment
  • Hypocalcemia
  • Hypophosphatemia
  • Hypomagnesemia

Seek medical help immediately.

Available Brands:

  • Hendronic
  • Osteomet
  • Vexonib-4
  • Zobone
  • Zoldron-4
  • Zolerix
  • Zoletero 4
  • Aclasta
  • Zoletalis
  • Zometa

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