ULTRAVIST

Do not use Ultravist in people with the following conditions:

• Hypersensitivity: Iopromide injection should not be used in individuals who have a known hypersensitivity or allergic reaction to iopromide or any other components of the formulation. Allergic reactions to contrast agents can range from mild skin rashes to severe anaphylactic reactions, which can be life-threatening
• Severe renal impairment: Iopromide injection is excreted primarily through the kidneys. Therefore, it should be used with caution or avoided altogether in individuals with severe renal impairment or end-stage renal disease. Impaired renal function can lead to the accumulation of the contrast agent, increasing the risk of nephrotoxicity.
• Thyroid disorders: Iopromide injection can interfere with thyroid function tests, leading to inaccurate results. Therefore, its use should be avoided in patients undergoing thyroid function testing.
• Acute pulmonary edema or heart failure: Iopromide injection can exacerbate the symptoms of acute pulmonary edema or heart failure. It can cause fluid overload and further compromise cardiac function. Therefore, its use should be avoided or used with caution in individuals with these conditions.
• Pheochromocytoma: Iopromide injection can stimulate the release of catecholamines, which can be dangerous in individuals with pheochromocytoma, a tumor of the adrenal glands. Its use in these patients should be carefully considered, and alternative imaging methods may be preferred.
• Pre-existing conditions: Iopromide injection should be used with caution in individuals with pre-existing medical conditions such as asthma, allergic disorders, or a history of severe allergic reactions. These individuals may be at higher risk of developing an allergic reaction to the contrast agent.
  It is crucial to inform your healthcare provider about any medical conditions, allergies, or medications you are taking before undergoing any procedure involving iopromide injection. They will carefully evaluate your individual circumstances and consider the potential risks and benefits to determine if the use of iopromide injection is appropriate for you.

Ultravist may have the following side effects:

• Allergic reactions: Allergic reactions to iopromide injection can occur, although they are relatively rare. Symptoms may include skin rash, itching, hives, swelling, difficulty breathing, and in severe cases, anaphylaxis. It is important to inform your healthcare provider immediately if you experience any signs of an allergic reaction.
• Nephrotoxicity: Iopromide injection can potentially cause kidney damage, particularly in individuals with pre-existing renal impairment or those who receive high doses of the contrast agent. Symptoms of nephrotoxicity may include changes in urine output, decreased kidney function, or kidney failure. Your healthcare provider will monitor your kidney function before and after the procedure to minimize the risk of this complication.
• Hypotension: Iopromide injection can cause a drop in blood pressure, leading to symptoms such as lightheadedness, dizziness, or fainting. This is more likely to occur in individuals who are dehydrated or have underlying cardiovascular conditions.
• Gastrointestinal discomfort: Some individuals may experience gastrointestinal side effects such as nausea, vomiting, or abdominal pain after receiving iopromide injection. These symptoms are usually mild and self-limiting.
• Headache: Headache is a relatively common side effect of iopromide injection. It is usually mild and transient, resolving on its own without specific treatment.
• Skin reactions: In rare cases, iopromide injection may cause skin reactions such as redness, swelling, or a localized rash at the injection site.
• Other side effects: Less commonly reported side effects of iopromide injection include fever, chills, altered taste sensation, blurred vision, and temporary visual disturbances.

Keep in mind that your physician has recommended this drug since he or she has known that the advantage to you is more noteworthy than the risk of adverse reactions. Many individuals utilizing this medicine don’t have serious side effects.

A serious allergy to this medication is uncommon. In any case, seek emergency medical help if you see any manifestations of a serious allergic response, including a rash, tingling or swelling particularly of the face or tongue or throat, dizziness or difficulty in breathing.

This is not a complete list of side effects. If you see other effects not recorded above, contact your physician or pharmacist.

Precautions

Take extra caution in patients with the following medical conditions:

• Renal function: Prior to the use of iopromide injection, it is important to assess the patient’s renal function. Individuals with pre-existing renal impairment or those at risk of developing contrast-induced nephropathy should be closely monitored. Adequate hydration before and after the procedure may help reduce the risk of kidney damage.
• Dehydration: Dehydration can increase the risk of kidney damage associated with iopromide injection. It is important to ensure adequate hydration before the procedure, especially in individuals who may be at risk, such as those with diabetes or elderly patients.
• Thyroid function: Iopromide injection can interfere with thyroid function tests, leading to inaccurate results. If thyroid function testing is planned, it is advisable to perform the test before the administration of iopromide injection.
• Medication interactions: It is important to inform your healthcare provider about all the medications you are taking, including prescription, over-the-counter, and herbal supplements. Some medications, such as metformin or nonsteroidal anti-inflammatory drugs (NSAIDs), may interact with iopromide injection and increase the risk of kidney damage. Your healthcare provider will determine if any adjustments or precautions are necessary.
• Pregnancy and breastfeeding: The use of iopromide injection during pregnancy should be carefully considered and discussed with your healthcare provider. While the risk to the developing fetus is generally low, the potential benefits and risks should be evaluated. It is also important to inform your healthcare provider if you are breastfeeding, as small amounts of iopromide may pass into breast milk.
• Pediatric and geriatric populations: Special precautions should be taken when using iopromide injection in pediatric and geriatric populations. Dose adjustments may be necessary based on the individual’s age, weight, and renal function.
• Contrast extravasation: Contrast extravasation occurs when the contrast agent leaks out of the blood vessel into the surrounding tissues during injection. It is important to monitor the injection site closely during the procedure to minimize the risk of extravasation

Prior to taking this medicine, tell your physician or pharmacist if you are allergic to it, or if you have some other hypersensitivities. This drug may contain inert ingredients which can cause unfavorable side effects or different issues. Talk with your pharmacist for more information.

Interactions

Ultravist may interact with the following medicines:

• Metformin: The combination of iopromide injection and metformin, a medication used to treat diabetes, may increase the risk of a serious condition called lactic acidosis. Your healthcare provider may recommend temporarily discontinuing metformin before the procedure and restarting it after ensuring your kidney function is stable.
• Nonsteroidal anti-inflammatory drugs (NSAIDs): NSAIDs, such as ibuprofen or naproxen, can potentially worsen kidney function when used in combination with iopromide injection. Your healthcare provider may advise avoiding NSAIDs for a certain period before and after the procedure to minimize this risk.
• Diuretics: Diuretics, which are medications that increase urine production, may further contribute to dehydration when used with iopromide injection. Adequate hydration is essential before and after the procedure, and your healthcare provider may adjust the dose or timing of your diuretic medication accordingly.
• Lithium: Iopromide injection can increase blood levels of lithium, a medication used to treat bipolar disorder. Your healthcare provider may monitor your lithium levels more closely if you are receiving iopromide injection
• Anticoagulants and antiplatelet medications: Iopromide injection can increase the risk of bleeding when used in combination with anticoagulants (e.g., warfarin) or antiplatelet medications (e.g., aspirin, clopidogrel). Your healthcare provider may assess the risks and benefits of continuing these medications before the procedure
• Other medications: There may be other medications that can potentially interact with iopromide injection. It is important to disclose your complete medication list to your healthcare provider to ensure safe and effective use of iopromide injection.

Inform your physician about the drugs you take including over-the-counter medications, prescribed drugs, supplements and vitamins.

This is not a complete list of drug interactions. Approach your physician or pharmacist for more details.

The effects of certain medications can change if you consume different medications or herbal products simultaneously. This can build your risk for side effects or may cause your drugs not to work effectively. These interactions are conceivable, yet don’t generally happen. Your physician or pharmacist can prevent or oversee interactions by changing how you utilize your prescriptions or by close checking.

While utilizing this drug, don’t start, stop, or change the dose of other medicines you are using without your physician’s advice.

If you suspect an overdose, contact your doctor right away.

Available Brands:

• Ultravist