HUMAN NORMAL IMMUNOGLOBULIN - Uses,Warnings,Side effects, Etc.


Human Normal Immunoglobulin is obtained from donated pooled human plasma. It contains antibodies, principally immunoglobulin G (IgG), that protect the body from different organisms and infections present in the community, such as hepatitis A, measles, mumps, rubella and varicella. It has IgG subclasses that is similar to that of the typical human plasma. It is used as vaccination against such diseases.

Use this medication precisely as recommended by your physician. Follow the prescription of your doctor carefully.

The medication dose your physician has given is based on your condition, other medications or food supplements you may take, and your reaction to treatment. To diminish your risks for adverse effects, don’t increase your dosage, take it regularly, or take it as instructed by your physician. Adverse events may still happen even at usual prescription dosages.

If your physician requests you to use this drug consistently, use it regularly to get the most benefits from it. To make you remember it better, take it at a fixed time every day.

Your doctor may need to modify your dosages to ease your symptoms or if you develop adverse reactions.

If you have any inquiries with regards to information, ask your physician or pharmacist.

Human Normal Immunoglobulin is used in the following conditions:

  • Prevent or modify measles attack in immunocompromised patients
  • Control outbreaks of hepatitis A
  • Primary rubella in pregnant women whereby pregnancy termination is unacceptable
  • Raise platelet count in patients with idiopathic thrombocytopenic purpura
  • Guillain-Barre syndrome
  • Kawasaki disease
  • Allogenic bone marrow transplantation
  • Prophylaxis of infections after bone marrow transplantation
  • Immunocompromised patients or patients with primary antibodies deficiency

This medicine may be recommended for different uses. Approach your physician or pharmacist for more information.

Do not use Human Normal Immunoglobulin in people with the following conditions:

  • Patients with selective immunoglobulin A deficiency
  • Prior anaphylactic reactions to immunoglobulin
  • Blood or other blood-derived preparations

Human Normal Immunoglobulin may have the following side effects:

  • Dizziness
  • Light-headedness
  • Nausea
  • Vomiting
  • Allergic and cutaneous reactions
  • Local pain and tenderness at the site of injection

Keep in mind that your physician has recommended this drug since he or she has known that the advantage to you is more noteworthy than the risk of adverse reactions. Many individuals utilizing this medicine don’t have serious side effects.

A serious allergy to this medication is uncommon. In any case, seek emergency medical help if you see any manifestations of a serious allergic response, including a rash, tingling or swelling particularly of the face or tongue or throat, dizziness or difficulty in breathing.

This is is not a complete list of side effects. If you see other effects not recorded above, contact your physician or pharmacist

Take extra caution in patients with the following medical conditions:

  • Increased risk of acute renal failure in patients with renal impairment
  • Diabetes mellitus
  • Hypovolemia
  • Overweight
  • Concomitant nephrotoxic medicinal products
  • Elderly greater than 65 years old
  • High infusion rate may increased risk of adverse reactions
  • Ensure adequate hydration prior to IVinfusion of immunoglobulin
  • Monitor urine output and serum creatinine levels during treatment
  • Avoid concurrent use of loop diuretics during IVinfusion of immunoglobulin
  • Live vaccines should generally be given 3 week before or 3 months after administrationof normal immunoglobulin
  • Different formulations and brands of human normal immunoglobulins may not be equivalent, thus individual literature should be consulted
  • Pregnancy
  • Lactation

Prior to taking this medicine, tell your physician or pharmacist if you are allergic to it, or if you have some other hypersensitivities. This drug may contain inert ingredients which can cause unfavorable side effects or different issues. Talk with your pharmacist for more information.


Human Normal Immunoglobulin may interact with the following medicines:

  • Live measles vaccine
  • Live mumps vaccine
  • Live rubella vaccine
  • Live varicella vaccine

Inform your physician about the drugs you take including over-the-counter medications, prescribed drugs, supplements and vitamins.

This is not a complete list of drug interactions. Approach your physician or pharmacist for more details.

The effects of certain medications can change if you consume different medications or herbal products simultaneously. This can build your risk for side effects or may cause your drugs not to work effectively. These interactions are conceivable, yet don’t generally happen. Your physician or pharmacist can prevent or oversee interactions by changing how you utilize your prescriptions or by close checking.

While utilizing this drug, don’t start, stop, or change the dose of other medicines you are using without your physician’s advice.

Symptoms of overdose may include the following:

  • Redness
  • Swelling and itching at injection site
  • Headache
  • Blood pressure changes
  • Nausea
  • Vomiting
  • Dizziness
  • Fever
  • Fatigue

Seek medical help immediately.

Available Brands:

  • Gamma I.V
  • Humoglob
  • Globu
  • Immunorel
  • Octagam 5%
  • Ig Vena

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