HUMAN NORMAL IMMUNOGLOBULIN

Human Normal Immunoglobulin is obtained from donated pooled human plasma. It contains antibodies, principally immunoglobulin G (IgG), that protect the body from different organisms and infections present in the community, such as hepatitis A, measles, mumps, rubella and varicella. It has IgG subclasses that is similar to that of the typical human plasma. It is used as vaccination against such diseases.

Use this medication precisely as recommended by your physician. Follow the prescription of your doctor carefully.

The medication dose your physician has given is based on your condition, other medications or food supplements you may take, and your reaction to treatment. To diminish your risks for adverse effects, don’t increase your dosage, take it regularly, or take it as instructed by your physician. Adverse events may still happen even at usual prescription dosages.

If your physician requests you to use this drug consistently, use it regularly to get the most benefits from it. To make you remember it better, take it at a fixed time every day.

Your doctor may need to modify your dosages to ease your symptoms or if you develop adverse reactions.

If you have any inquiries with regards to information, ask your physician or pharmacist.

Uses

Human Normal Immunoglobulin is used in the following conditions:

Prevent or modify measles attack in immunocompromised patients
Control outbreaks of hepatitis A
Primary rubella in pregnant women whereby pregnancy termination is unacceptable
Raise platelet count in patients with idiopathic thrombocytopenic purpura
Guillain-Barre syndrome
Kawasaki disease
Allogenic bone marrow transplantation
Prophylaxis of infections after bone marrow transplantation
Immunocompromised patients or patients with primary antibodies deficiency

This medicine may be recommended for different uses. Approach your physician or pharmacist for more information.

Warnings

Do not use Human Normal Immunoglobulin in people with the following conditions:

Patients with selective immunoglobulin A deficiency
Prior anaphylactic reactions to immunoglobulin
Blood or other blood-derived preparations

Side Effects

Human Normal Immunoglobulin may have the following side effects:

Dizziness
Light-headedness
Nausea
Vomiting
Allergic and cutaneous reactions
Local pain and tenderness at the site of injection

Keep in mind that your physician has recommended this drug since he or she has known that the advantage to you is more noteworthy than the risk of adverse reactions. Many individuals utilizing this medicine don’t have serious side effects.

A serious allergy to this medication is uncommon. In any case, seek emergency medical help if you see any manifestations of a serious allergic response, including a rash, tingling or swelling particularly of the face or tongue or throat, dizziness or difficulty in breathing.

This is is not a complete list of side effects. If you see other effects not recorded above, contact your physician or pharmacist

Precautions

Take extra caution in patients with the following medical conditions:

Increased risk of acute renal failure in patients with renal impairment
Diabetes mellitus
Hypovolemia
Overweight
Concomitant nephrotoxic medicinal products
Elderly greater than 65 years old
High infusion rate may increased risk of adverse reactions
Ensure adequate hydration prior to IVinfusion of immunoglobulin
Monitor urine output and serum creatinine levels during treatment
Avoid concurrent use of loop diuretics during IVinfusion of immunoglobulin
Live vaccines should generally be given 3 week before or 3 months after administrationof normal immunoglobulin
Different formulations and brands of human normal immunoglobulins may not be equivalent, thus individual literature should be consulted
Pregnancy
Lactation

Prior to taking this medicine, tell your physician or pharmacist if you are allergic to it, or if you have some other hypersensitivities. This drug may contain inert ingredients which can cause unfavorable side effects or different issues. Talk with your pharmacist for more information.

Interactions

Human Normal Immunoglobulin may interact with the following medicines:

Live measles vaccine
Live mumps vaccine
Live rubella vaccine
Live varicella vaccine

Inform your physician about the drugs you take including over-the-counter medications, prescribed drugs, supplements and vitamins.

This is not a complete list of drug interactions. Approach your physician or pharmacist for more details.

The effects of certain medications can change if you consume different medications or herbal products simultaneously. This can build your risk for side effects or may cause your drugs not to work effectively. These interactions are conceivable, yet don’t generally happen. Your physician or pharmacist can prevent or oversee interactions by changing how you utilize your prescriptions or by close checking.

While utilizing this drug, don’t start, stop, or change the dose of other medicines you are using without your physician’s advice.

Overdose & Brands

Symptoms of overdose may include the following:

Redness
Swelling and itching at injection site
Headache
Blood pressure changes
Nausea
Vomiting
Dizziness
Fever
Fatigue

Seek medical help immediately.

Available Brands:

Gamma I.V
Humoglob
Globu
Immunorel
Octagam 5%
Ig Vena