Watsons Health

ALLOPURINOL

Allopurinol is used for treating hyperuricaemia and gout. It reduces the formation of uric acid in purine metabolism without disturbing the production of important purines.

Allopurinol minimizes uric acid formation by blocking xanthine oxidase that acts as a catalyst in converting hypoxanthine to xanthine and finally to uric acid. As it blocks xanthine oxidase enzyme, uric acid production will be considerably reduced.

Allopurinol is prescribed to treat gout and hyperuricaemia.

Do not give this drug to people with the following conditions:

  • Acute gout attack
  • Renal and hepatic impairment
  • Pregnancy and lactation

Allopurinol may have the following side effects:

Precautions

Take extra caution in patients with the following medical conditions:

  • Renal and hepatic impairment
  • Pregnancy and lactation

 

Interactions

Allopurinol may interact with the following medicines:

  • Mercaptopurine
  • Azathioprine
  • Warfarin and other coumarin anticoagulants
  • Salicylates or uricosuric agents
  • Thiazide diuretics,
  • Some antibacterials
  • Antineoplastics
  • Ciclosporin
  • Sulfonylurea antidiabetics
  • Theophylline
  • Vidarabine

If you think you have used  Allopurinol drug more than the normal dosage, please seek medical help immediately.

 

Available Brands:

Allurase, Alpurase, Llanol, Loricid, Prinol, Purinase, RiteMED Al and Urinol Zyloprim

Related Articles

LESINURAD

Lesinurad suppresses the enzymes uric acid transporter 1 (URAT1) and organic anion carrier 4 (OAT4), which increases uric acid outflow [...]

LEMBOREXANT

Lemborexant is an orexin potent inhibitor that's competitive. It is considered to prevent the attachment of wake-promoting neurotrophins orexin A [...]

INSULIN LISPRO + INSULIN LISPRO PROTAMINE

Insulin lispro is a fast-acting human insulin alternative, whereas insulin lispro protamine is a slow-acting human insulin alternative. They both [...]