Octocog Alfa is also known as coagulation factor VIII, recombinant is a glycoprotein that is naturally compared to the factor VIII glycoprotein that is found in human plasma. It attaches to endogenous von Willebrand Factor in the patient’s blood. Activated factor VIII initiates factor X, as co-factor for activated factor IX. Activated factor X changes prothrombin to thrombin, which changes over fibrinogen to fibrin, bringing about steady coagulation.
It is a kind of drug which is structurally and functionally similar to a previously marketed, albumin-containing formulation of the same recombinant factor VIII. The hemostatic efficacy of octocog alfa-PFM was graded as excellent or good in the acute treatment of most breakthrough bleeding episodes in adolescents or adults with slightly severe and severe hemophilia. A who were receiving prophylaxis with this kind of drug and who had been already treated with factor VII. Most bleeding sessions settled after one or two infusions of octocog alfa-PFM.
This drug also has side effects. The usual side effects are an itchy skin rash, redness, and soreness at the area of the injection. If you are breastfeeding or pregnant, try to consult a doctor first if you can use it. Always follow the instructions of the doctor or pharmacist. If an overdose occurs, medical attention is needed immediately.
