DEXTROPROPOXYPHENE

Dextropropoxyphene is a drug that is considered to be a weak opioid analgesic that binds to mu- and kappa-receptors to block pain signals in the cerebral cortex. This leads to pain relief.

Uses

Dextropropoxyphene is used in the relief of mild to moderate pain.

Warnings

Dextropropoxyphene should not be used in people with the following medical conditions:

Hypersensitivity
Chronic lung diseases
Porphyria
Pregnancy
Patients on monoamine oxidase inhibitors (MAOI) treatment or within 2 weeks of stopping treatment

Side Effects

Dextropropoxyphene can bring about the following side effects:

Dizziness
Sedation
Weakness
Nausea
Vomiting
Constipation
Rash
Urticaria
Visual disturbances
Physiological dependence
Convulsions in long-term therapy
Cardiac conduction abnormalities and arrhythmias
Liver impairment

Precautions

Precautions

Special precautions should be observed by the following:

Suicidal patients
Hepatic or renal disease
Lactation
Elderly

Interactions

Dextropropoxyphene can interact with the following medicines:

Benzodiazepines
β-blockers
Carbamazepine
Phenytoin
Warfarin
Ritonavir
Alcohol or other central nervous system (CNS) depressants

Overdose & Brands

Symptoms of Dextropropoxyphene overdose include the following:

Coma
Respiratory depression
Circulatory collapse
Pulmonary edema
Seizures
Nephrogenic diabetes insipidus
ECG abnormalities
Death may occur as early within the first 15 minutes to 1 hour

Seek medical help immediately.

Available Brands:

Darvon