Atosiban - Uses, Warnings, Side Effects, Precautions, Overdose,Etc.


Atosiban is a synthetic oxytocin peptide analogue which inhibits the effects of oxytocin and vasopressin. It suppresses uterine contractions by reducing its frequency and the tone of uterine musculature to delay premature birth in adult females.

Use this medication precisely as recommended by your physician. Follow the prescription of your doctor carefully.

The medication dose given by your physician is based on your health conditions, other medications or food supplements taken, and your reaction to the treatment. To diminish risks for adverse effects, do not increase your dosage, thus take it regularly, or take it as instructed by your physician. Adverse events may still happen even at usual prescription dosages.

If your physician requests you to use this drug consistently, take it regularly to get the most benefits from it. To make you remember it better, take it at a fixed time every day.

Your doctor may need to modify your dosages to ease your symptoms or if you develop adverse reactions.

If you have any inquiries with regards to information, ask your physician or pharmacist.

Atosiban is used in the following conditions:

  • Premature labor

This medicine may be recommended for different uses. Approach your physician or pharmacist for more information.

Do not use Atosiban in people with the following conditions:

  • Gestational age not less than 24 weeks or not more than 33 weeks
  • Premature rupture of membranes not more than 30 weeks of gestation
  • Uterine hemorrhage requiring immediate delivery
  • Eclampsia
  • Severe pre-eclampsia
  • Intra-uterine growth retardation withabnormal fetal heart rate
  • Intra-uterine fetal death
  • Suspected intra-uterine infection
  • Placenta praevia(abnormal position of placenta)
  • Abruptio placentae(premature separation of the placenta from the uterus)

Atosiban may have the following side effects:

  • Nausea
  • Vomiting
  • Headache
  • Dizziness
  • Flushes
  • Tachycardia
  • Hypotension
  • Hyperglycemia

Injection site reactions:

  • Insomnia
  • Pruritus
  • Rash
  • Pyrexia


  • Uterine hemorrhage
  • Atony


Keep in mind that your physician has recommended this drug since he or she has known that the advantage to you is more significant than the risk of adverse reactions. Many individuals utilizing this medicine don’t have serious side effects.

A severe allergy to this medication is uncommon. In any case, seek emergency medical help if you see any manifestations of a serious allergic response, including a rash, tingling or swelling particularly of the face or tongue or throat, dizziness or difficulty in breathing.

This is not a complete list of side effects. If you see other effects not recorded above, contact your physician or pharmacist.


Take extra caution in patients with the following medical conditions:

  • Patient withabnormal placental site
  • Intra-uterine growth restriction
  • Multiple pregnancy
  • Hepatic impairment
  • Lactation

Prior in taking this medicine, tell your physician or pharmacist if you have allergies  or other hypersensitivity reactions with the drug. This drug may contain inert ingredients which can cause unfavorable side effects or different issues. Talk with your pharmacist for more information.



Atosiban may interact with the following medicines:

  • Increased risk of pulmonary edema withother tocolytic drugs

Inform your physician about the drugs you take including over-the-counter medications, prescribed drugs, supplements and vitamins.

This is not a complete list of drug interactions. Approach your physician or pharmacist for more details.

The effects of certain medications can change if you consume different medications or herbal products simultaneously. This can build your risk for side effects or may cause your drugs not to work effectively. These interactions are possible, yet don’t generally happen. Your physician or pharmacist can prevent or oversee interactions by changing how you utilize your prescriptions or by close checking.

While utilizing this drug, don’t start, stop, or change the dose of other medicines you are using without your physician’s advice.

If overdose is suspected call your health care provider immediately.

Available Brands:

  • Evaban
  • Tractocile

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