THIOCOLCHICOSIDE - Watsons Health

THIOCOLCHICOSIDE

Thiocolchicoside is a muscle relaxant with anti-inflammatory and analgesic effects. It acts as a competitive GABA-A receptor antagonist and also glycine receptor antagonist with similar potency and nicotinic acetylcholine receptors to a much lesser extent.

Thiocolchicoside is used as a muscle relaxant in the treatment of painful muscular conditions. It is thought to act on receptors in the nervous system that are involved in the regulation of muscle function.

Intramuscular administration is contraindicated in patients receiving anti-coagulant therapy and in patients with bleeding.

Thiocolchicoside should not be used in patients with severe renal failure.

Thiocolchicoside may give rise to the following side effects:

  • Abdominal cramps
  • Abdominal bloating
  • Abdominal pain
  • Diarrhea
  • Dizziness
  • Fatigue
  • Headache
  • Influenza like symptoms
  • Nausea
  • Weakness
  • Photosensitivity

Precautions

Caution should be taken while using this medication in those with the following conditions:

  • Known hypersensitivity to benzodiazepines
  • Acute closed-angle glaucoma
  • Myasthenia gravis
  • Liver or kidney disease
  • History of alcohol or substance abuse
  • Chronic lung disease
  • Epilepsy
  • Mental illness or depression
  • Sleep apnoea

 

Interactions

No data regarding the interactions of Thiocolchicoside was found

Although muscle relaxants may have the major side effect of sedation, thiocholchicoside is free from sedation effects possible due to non-interference with nicotinic receptors.

 

Available Brands:

Muscoril, Myoril, Neoflax

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