THIOCOLCHICOSIDE

Thiocolchicoside is a muscle relaxant with anti-inflammatory and analgesic effects. It acts as a competitive GABA-A receptor antagonist and also glycine receptor antagonist with similar potency and nicotinic acetylcholine receptors to a much lesser extent.

Uses

Thiocolchicoside is used as a muscle relaxant in the treatment of painful muscular conditions. It is thought to act on receptors in the nervous system that are involved in the regulation of muscle function.

Warnings

Intramuscular administration is contraindicated in patients receiving anti-coagulant therapy and in patients with bleeding.

Thiocolchicoside should not be used in patients with severe renal failure.

Side Effects

Thiocolchicoside may give rise to the following side effects:

Abdominal cramps
Abdominal bloating
Abdominal pain
Diarrhea
Dizziness
Fatigue
Headache
Influenza like symptoms
Nausea
Weakness
Photosensitivity

Precautions

Precautions

Caution should be taken while using this medication in those with the following conditions:

Known hypersensitivity to benzodiazepines
Acute closed-angle glaucoma
Myasthenia gravis
Liver or kidney disease
History of alcohol or substance abuse
Chronic lung disease
Epilepsy
Mental illness or depression
Sleep apnoea

Interactions

No data regarding the interactions of Thiocolchicoside was found

Overdose & Brands

Although muscle relaxants may have the major side effect of sedation, thiocholchicoside is free from sedation effects possible due to non-interference with nicotinic receptors.

Available Brands:

Muscoril, Myoril, Neoflax