TERCONAZOLE

COMMON BRAND NAME(S): Terazol 7

GENERIC NAME(S): TERCONAZOLE

 

Description: Terconazole is an antifungal that works by disrupting ergosterol. It has some antibacterial activity in vitro but not against usual vag flora e.g. lactobacilli.

Pharmacokinetics:

Absorption: Absorbed systemically (5-16%).

Metabolism: Metabolised hepatically.

Excretion: Via urine and faeces.

This medication is an azole antifungal used to treat vaginal yeast infections. By stopping the growth of yeast (fungus) that causes the infection, Terconazole reduces vaginal burning, itching, and discharge that may occur with this condition.

How to use terconazole vaginal

Read the Patient Information Leaflet if available from your pharmacist before you start using terconazole, and each time you get a refill. If you have any questions regarding the information, consult your doctor or pharmacist.

This product is for vaginal use only. Wash your hands before and after use. Avoid contact with your eyes. If it gets into your eyes, wash them immediately with plenty of water. Call your doctor if eye irritation persists.

Use this product usually once daily at bedtime for 3 or 7 days (depending on product) or as directed by your doctor. The dosage and length of treatment is based on your medical condition and response to treatment.

Learn all preparation and usage instructions in the product package. If using the cream, use the applicator. If using the suppository, you may use either the applicator or your finger to insert it. Unwrap the suppository before use. Follow the package instructions on how to fill the applicator with the cream or with a suppository. Lie on your back with your knees toward your chest. Insert the applicator or suppository into the vagina as far as it will comfortably go. Slowly press the plunger of the applicator in to release the medication. Clean the applicator with warm soapy water, rinse well, and dry. If you have itching/burning around the outside of the vagina (vulva), you may also apply terconazole cream once daily to that area and rub in.

Continue to use this medication every day until the full prescribed amount is finished, even if symptoms disappear after 1 to 2 days. Stopping the medication too soon may allow the yeast to continue to grow, which may result in a return of the infection.

You may use this product during your menstrual period. Do not use tampons or douches while using this medication. Unscented sanitary napkins may be used for your menstrual period or to protect your clothing from leakage of the medication.

Tell your doctor if your condition does not improve or if it returns within 2 months. You may need a different or additional medication to treat your condition.

Not available.

Notify your doctor or pharmacist promptly if any of these effects persist or worsen:

  • headache
  • increased vaginal/urethral burning/itching/pain
  • menstrual cramps

Flu-like symptoms (including fever/chills), foul-smelling discharge from the vagina, or stomach/abdominal pain may be side effects. However, they may also be symptoms of a different or more serious condition (bacterial vaginosis or Pelvic Inflammatory Disease-PID) that may require different treatment.

A very serious allergic reaction to this drug is unlikely, but seek immediate medical attention if it occurs.

This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.

Precautions:

  • Allergic reaction to this medication
  • Patients with medical history of:
    • Diabetes
    • immune system problems (such as HIV-AIDS)
    • frequent vaginal yeast infections (more than 4 per year)
  • Tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products) before having surgery
  • Ask your doctor whether you can have sexual intercourse while using this product
  • This medication should be used only when clearly needed during pregnancy
  • Discuss the risks and benefits with your doctor before breast-feeding

Consult your doctor regarding the precautions mentioned above.

Interactions:

Antibiotics, corticosteroids (such as prednisone), and drugs that suppress the immune system (such as cyclosporine, methotrexate)may increase the risk of vaginal yeast infections.

Overdose:

This medicine may be harmful if swallowed. If swallowing or overdose is suspected, contact a poison control center or emergency room immediately.

Notes

Do not share this medication with others.

To help prevent vaginal yeast infections, dry the genital area thoroughly after showering, bathing, or swimming. Avoid wearing tight jeans, nylon underwear, pantyhose, a wet bathing suit, or damp/sweaty exercise clothes for long periods. Wear cotton underwear, and change your underwear daily.

This medication has been prescribed for your current condition only. Do not use it later for another infection unless told to do so by your doctor. A different medication may be necessary in that case.

If your sexual partner experiences symptoms, they should contact their doctor immediately.

Missed Dose

If you miss a dose, use it as soon as you remember. If it is near the time of the next dose, skip the missed dose and resume your usual dosing schedule. Do not double the dose to catch up.

Storage

Store the cream or suppository at room temperature away from light and moisture. Do not store in the bathroom. Keep all medicines away from children and pets.

Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company.

Brands:

There are no brands containing this molecule.

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