TENIPOSIDE

Teniposide is a semisynthetic derivative of podophyllotoxin which has antineoplastic properties similar to etoposide. It appears to produce its cytotoxic effects by inhibiting or altering the DNA synthesis and prevents cell mitosis by breaking the single and double stranded DNA as well as cross linking between protein and DNA.

Use this medication precisely as recommended by your physician. Follow the prescription of your doctor carefully.

The medication dose given by your physician is based on your health conditions, other medications or food supplements taken, and your reaction to the treatment. To diminish risks for adverse effects, do not increase your dosage, thus take it regularly, or take it as instructed by your physician. Adverse events may still happen even at usual prescription dosages.

If your physician requests you to use this drug consistently, take it regularly to get the most benefits from it. To make you remember it better, take it at a fixed time every day.

Your doctor may need to modify your dosages to ease your symptoms or if you develop adverse reactions.

Uses

Teniposide is used in the following conditions:

Refractory acute lymphoblastic leukemia

Warnings

Do not use Teniposide in people with the following conditions:

Hypersensitivity to polyoxyethylated castor oil
Pregnancy
Lactation
Severe hepatic and renal failure

Side Effects

Teniposide may have the following side effects:

Reversible alopecia
Nausea
Vomiting
Diarrhea
Mucositis
Rash
Fever
Neurotoxicity
Hepatic or renal dysfunction
Infection
Bleeding
Secondary acute myeloid leukemia
Hypotension upon rapid IV

Potentially fatal:

Severe hypersensitivity reactions

Keep in mind that your physician has recommended this drug since he or she has known that the advantage to you is more significant than the risk of adverse reactions. Many individuals utilizing this medicine don’t have serious side effects.

A severe allergy to this medication is uncommon. In any case, seek emergency medical help if you see any manifestations of a serious allergic response, including a rash, tingling or swelling particularly of the face or tongue or throat, dizziness or difficulty in breathing.

This is not a complete list of side effects. If you see other effects not recorded above, contact your physician or pharmacist.

Precautions

Take extra caution in patients with the following medical conditions:

Monitor CBC and electrolytes
Monitor renal and hepatic function at baseline and before each treatment
Avoid extravasation
Reduce dose in down’s syndrome
Hepatic and renal impairment

Prior in taking this medicine, tell your physician or pharmacist if you have allergies or other hypersensitivity reactions with the drug. This drug may contain inert ingredients which can cause unfavorable side effects or different issues. Talk with your pharmacist for more information.

Interactions

Teniposide may interact with the following medicines:

Phenytoin
Phenobarbital
Carbamazepine
Ciclosporin
Zidovudine
Digoxin
Vaccines

Inform your physician about the drugs you take including over-the-counter medications, prescribed drugs, supplements and vitamins.

This is not a complete list of drug interactions. Approach your physician or pharmacist for more details.

The effects of certain medications can change if you consume different medications or herbal products simultaneously. This can build your risk for side effects or may cause your drugs not to work effectively. These interactions are possible, yet don’t generally happen. Your physician or pharmacist can prevent or oversee interactions by changing how you utilize your prescriptions or by close checking.

While utilizing this drug, don’t start, stop, or change the dose of other medicines you are using without your physician’s advice.

Overdose & Brands

If you think you have used Teniposide more than the usual dosage, please seek medical help immediately.

Symptoms of overdose may include the following:

Slowed breathing
Excessive tiredness
Slow or irregular heartbeat
Confusion
Fainting
Dizziness
Blurred vision
Fever
Sore throat
Chills
Ongoing cough and congestion
Other signs of infection
Unusual bleedingand bruising

Available Brands:

Vumon