Indications: | Respiratory stimulant. |
Dosage: | Adult : PO 100 mg 3 times/day. |
Dosage Details: | Oral Respiratory stimulantAdult: 100 mg tid. |
Contraindications: | Epilepsy or other convulsive disorders, cerebral oedema, cerebrovascular accident, head injury, acute severe asthma, physical obstruction of the airway, severe hypertension, ischaemic heart disease, hyperthyroidism, pheochromocytoma. |
Special Precautions: | mild-moderate hypertension, impaired cardiac reserve; liver or renal dysfunction. |
Adverse Drug Reactions: | Dyspnoea, resp problems; muscular, GI, CNS and CV effects.
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Drug Interactions: | Concurrent use with anaesthetics may cause cardiac arrhythmias. Increased pressor effects when used with sympathomimetics or MAOIs. May mask the residual effects of neuromuscular blockers.
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Mechanism of Action: | Description: Prethcamide is a central and resp stimulant with a brief duration of action. It acts by stimulation of peripheral chemoreceptors and central resp centers. It has pressor effects and may also increase catecholamine release. |
Therapeutic Category: | Respiratory Stimulants |