PANTAZO

Do not use Pantazo in people with the following conditions:

• Hypersensitivity
• History of liver dysfunction: Piperacillin + Tazobactam is primarily eliminated from the body through the liver. Therefore, individuals with severe liver dysfunction may need dosage adjustments or close monitoring when using this medication.
• History of bleeding disorders: Piperacillin + Tazobactam can potentially increase the risk of bleeding due to its effect on platelet function. Individuals with a history of bleeding disorders or those taking medications that affect blood clotting should use Piperacillin + Tazobactam with caution.

It is important to discuss your medical history, allergies, and any current medications with your healthcare provider before starting Piperacillin + Tazobactam. They will be able to evaluate your individual situation and determine whether this medication is safe and appropriate for you. If you have any concerns or questions, it is always best to consult with a healthcare professional.

Pantazo may have the following side effects:

• Gastrointestinal effects: The most common side effects include nausea, vomiting, diarrhea, and abdominal pain. These symptoms are generally mild and resolve on their own.
• Allergic reactions: Some individuals may develop allergic reactions to Piperacillin + Tazobactam, ranging from mild rashes to severe hypersensitivity reactions like anaphylaxis. Seek immediate medical attention if you experience difficulty breathing, swelling of the face or throat, or a severe skin rash.
• Skin reactions: Skin rash or itching may occur in some individuals. If you notice any skin changes while taking Piperacillin + Tazobactam, inform your healthcare provider.
• Liver function abnormalities: In rare cases, Piperacillin + Tazobactam may cause liver function abnormalities, such as increased liver enzymes. This is more likely in individuals with pre-existing liver disease.
• Blood disorders: Piperacillin + Tazobactam may rarely cause blood disorders, such as decreased white blood cell count (leukopenia), decreased platelet count (thrombocytopenia), or anemia. These side effects are usually reversible after discontinuing the medication.
• Central nervous system effects: Some individuals may experience headache, dizziness, or confusion while taking Piperacillin + Tazobactam. If these symptoms are severe or persistent, it is advisable to consult your healthcare provider.

Keep in mind that your physician has recommended this drug since he or she has known that the advantage to you is more noteworthy than the risk of adverse reactions. Many individuals utilizing this medicine don’t have serious side effects.

A serious allergy to this medication is uncommon. In any case, seek emergency medical help if you see any manifestations of a serious allergic response, including a rash, tingling or swelling particularly of the face or tongue or throat, dizziness or difficulty in breathing.

This is not a complete list of side effects. If you see other effects not recorded above, contact your physician or pharmacist.

Precautions

Take extra caution in patients with the following medical conditions:

• Allergies: Inform your healthcare provider if you have any known allergies to Piperacillin, Tazobactam, or any other beta-lactam antibiotics (such as penicillins or cephalosporins). Allergic reactions can range from mild rashes to severe hypersensitivity reactions. Caution should be exercised if you have a history of allergies.
• Kidney function: Piperacillin + Tazobactam is primarily eliminated from the body through the kidneys. If you have impaired kidney function, your healthcare provider may need to adjust the dosage or monitor your kidney function closely during treatment.
• Seizure disorders: Piperacillin + Tazobactam may rarely lower the seizure threshold. If you have a history of seizure disorders or conditions that increase the risk of seizures, caution should be exercised, and the benefits and risks of using this medication should be carefully evaluated.
• Clostridium difficile infection: Antibiotics like Piperacillin + Tazobactam can disrupt the normal balance of bacteria in the gut and potentially lead to a Clostridium difficile infection. If you experience severe diarrhea or abdominal pain during or after treatment, inform your healthcare provider, as this could be a sign of this infection.
• Pregnancy and breastfeeding: It is important to inform your healthcare provider if you are pregnant, planning to become pregnant, or breastfeeding. The use of Piperacillin + Tazobactam during pregnancy or breastfeeding should be carefully evaluated by your healthcare provider, weighing the potential benefits against the potential risks.

Prior to taking this medicine, tell your physician or pharmacist if you are allergic to it, or if you have some other hypersensitivities. This drug may contain inert ingredients which can cause unfavorable side effects or different issues. Talk with your pharmacist for more information.

Interactions

Pantazo may interact with the following medicines:

• Probenecid: Probenecid can increase the blood levels of Piperacillin by reducing its elimination from the body. This can potentially increase the risk of side effects. Your healthcare provider may need to adjust the dosage of Piperacillin + Tazobactam if you are taking probenecid.
• Methotrexate: Piperacillin + Tazobactam may increase the blood levels of methotrexate, a medication used to treat certain cancers and autoimmune conditions. This can potentially increase the risk of methotrexate toxicity. Close monitoring of methotrexate levels and potential adjustments in its dosage may be necessary when used concomitantly with Piperacillin + Tazobactam.
• Anticoagulants: Piperacillin + Tazobactam may enhance the effects of anticoagulant medications, such as warfarin, leading to an increased risk of bleeding. Regular monitoring of blood clotting parameters is important if you are taking both medications.
• Other antibiotics: Concurrent use of Piperacillin + Tazobactam with other antibiotics, such as aminoglycosides or vancomycin, may have additive or synergistic effects against certain bacteria. However, the combination should be used cautiously, and your healthcare provider will determine the appropriate dosages and duration of treatment.
• Oral contraceptives: Piperacillin + Tazobactam may reduce the effectiveness of hormonal contraceptives, such as birth control pills. It is recommended to use additional contraceptive methods while taking this medication and for a short period after completing the treatment.It’s important to note that this is not an exhaustive list of interactions.

Inform your physician about the drugs you take including over-the-counter medications, prescribed drugs, supplements and vitamins.

This is not a complete list of drug interactions. Approach your physician or pharmacist for more details.

The effects of certain medications can change if you consume different medications or herbal products simultaneously. This can build your risk for side effects or may cause your drugs not to work effectively. These interactions are conceivable, yet don’t generally happen. Your physician or pharmacist can prevent or oversee interactions by changing how you utilize your prescriptions or by close checking.

While utilizing this drug, don’t start, stop, or change the dose of other medicines you are using without your physician’s advice.

If you suspect an overdose, contact your doctor right away.

Available Brands:

• Pantazo