ODAFT

Do not use Odaft in people with the following conditions:

• Hypersensitivity: Fluconazole should not be used in individuals who have a known hypersensitivity or allergy to fluconazole or any of its components.
• Pregnancy and breastfeeding: Fluconazole is generally not recommended during pregnancy, particularly during the first trimester, unless the potential benefits outweigh the risks. High doses of fluconazole may be associated with an increased risk of birth defects  Additionally, fluconazole can pass into breast milk, so it is important to consult with a healthcare provider before using fluconazole while breastfeeding.
• Liver dysfunction: Fluconazole is primarily metabolized in the liver, so individuals with severe liver dysfunction should use fluconazole with caution. Dosage adjustments may be necessary in these cases.
• Heart conditions: Fluconazole may prolong the QT interval, which can increase the risk of abnormal heart rhythms. It is contraindicated in individuals with known QT prolongation or those who are taking other medications that can prolong the QT interval.

Like any medication, fluconazole can cause side effects. Common side effects of fluconazole may include:

• Nausea and vomiting
• Abdominal pain
• Diarrhea
• Headache
• Rash or skin reactions
• Dizziness
• Changes in taste sensation
• Increased liver enzymes
• Elevated levels of blood cholesterol or triglycerides
• Fatigue or weakness

These side effects are usually mild and go away on their own. However, if any of these side effects persist or worsen, it is important to consult with your healthcare provider.

In rare cases, fluconazole can cause more serious side effects. These may include:

• Allergic reactions: Some individuals may experience severe allergic reactions such as rash, itching, swelling, severe dizziness, or difficulty breathing. Seek immediate medical attention if you experience any of these symptoms.
• Liver problems: Fluconazole can occasionally cause liver damage, leading to symptoms such as yellowing of the skin or eyes, dark urine, or persistent nausea and vomiting. If you experience these symptoms, contact your healthcare provider immediately.
• Serious skin reactions: Rarely, fluconazole can cause serious skin reactions such as Stevens-Johnson syndrome or toxic epidermal necrolysis, which require immediate medical attention.

Keep in mind that your physician has recommended this drug since he or she has known that the advantage to you is more noteworthy than the risk of adverse reactions. Many individuals utilizing this medicine don’t have serious side effects.

A serious allergy to this medication is uncommon. In any case, seek emergency medical help if you see any manifestations of a serious allergic response, including a rash, tingling or swelling particularly of the face or tongue or throat, dizziness or difficulty in breathing.

This is not a complete list of side effects. If you see other effects not recorded above, contact your physician or pharmacist.

Precautions

Take extra caution in patients with the following medical conditions:

• Allergies: Inform your healthcare provider if you have any known allergies to fluconazole or any other antifungal medications. Allergic reactions can be serious, so it is important to avoid fluconazole if you have a known allergy.
• Medical history: Discuss your medical history with your healthcare provider, especially if you have any liver disease, kidney disease, heart conditions, or any other underlying health conditions. Fluconazole may require dosage adjustments or close monitoring in these cases.
• Drug interactions: Inform your healthcare provider about all the medications you are currently taking, including prescription, over-the-counter drugs, and herbal supplements. Certain medications can interact with fluconazole and affect its effectiveness or increase the risk of side effects.
• Pregnancy and breastfeeding: If you are pregnant or planning to become pregnant, discuss the use of fluconazole with your healthcare provider. Depending on the situation, the benefits and risks of using fluconazole during pregnancy will be evaluated. Fluconazole can pass into breast milk, so it is important to consult with your healthcare provider if you are breastfeeding.
• Alcohol: It is generally recommended to avoid excessive alcohol consumption while taking fluconazole. Alcohol can increase the risk of liver damage and may interfere with the effectiveness of the medication.
• Driving and operating machinery: Fluconazole may cause dizziness or drowsiness in some individuals. If you experience these side effects, it is important to avoid driving or operating machinery until you know how the medication affects you.
• Follow dosage instructions: Take fluconazole exactly as prescribed by your healthcare provider. Do not change the dosage or stop taking the medication without consulting your healthcare provider.
• Store properly: Store fluconazole at room temperature, away from moisture and heat. Follow the storage instructions provided by the manufacturer.

Prior to taking this medicine, tell your physician or pharmacist if you are allergic to it, or if you have some other hypersensitivities. This drug may contain inert ingredients which can cause unfavorable side effects or different issues. Talk with your pharmacist for more information.

Interactions

Odaft may interact with the following medicines:

• Warfarin: Fluconazole can increase the blood-thinning effects of warfarin, which may lead to an increased risk of bleeding. Close monitoring of blood clotting times is recommended if these medications are used together.
• Certain anticoagulants and antiplatelet drugs: Similar to warfarin, fluconazole may increase the risk of bleeding when used with other anticoagulant or antiplatelet medications. Close monitoring is advised.
• Certain anticonvulsants: Fluconazole may increase the blood levels of some anticonvulsant medications, such as phenytoin or carbamazepine. Dose adjustments or monitoring may be necessary to maintain therapeutic levels.
• Certain immunosuppressant drugs: Fluconazole can increase blood levels of immunosuppressant medications like tacrolimus or cyclosporine, which may increase the risk of side effects. Monitoring and dose adjustments may be needed.
• Certain statins: Fluconazole may increase the blood levels of some statin medications, such as atorvastatin or simvastatin, potentially increasing the risk of muscle-related side effects. Dose adjustments or alternatives may be considered.
• Certain antidiabetic drugs: Fluconazole can affect blood sugar levels and may require adjustments in the dosage of antidiabetic medications, such as sulfonylureas or insulin.
• Benzodiazepines: Fluconazole can increase the blood levels of benzodiazepines like midazolam or triazolam, potentially causing increased sedation. Dose adjustments may be necessary.

Inform your physician about the drugs you take including over-the-counter medications, prescribed drugs, supplements and vitamins.

This is not a complete list of drug interactions. Approach your physician or pharmacist for more details.

The effects of certain medications can change if you consume different medications or herbal products simultaneously. This can build your risk for side effects or may cause your drugs not to work effectively. These interactions are conceivable, yet don’t generally happen. Your physician or pharmacist can prevent or oversee interactions by changing how you utilize your prescriptions or by close checking.

While utilizing this drug, don’t start, stop, or change the dose of other medicines you are using without your physician’s advice.

If you suspect an overdose, contact your doctor right away.

Available Brands:

• Odaft