KETOCONAZOLE + ZINC - Watsons Health


This drug is used to treat skin irritations such as seborrheic dermatitis, a form of dandruff. Ketoconazole is an azole antifungal drug that works by preventing the growth of fungus.

Ketoconazole / Zinc Pyrithione is used for fungal infections, yeast infections of skin, and other different conditions. This salt combination can also be used for purposes not listed on this medication guide.

Ketoconazole / Zinc Pyrithione is used for the treatment, management, prevention, and improvement of the following conditions:

  • Fungal infections
  • Yeast infections of skin
  • Other skin diseases

Inform your physician if you have the following:

  • Have or history of hepatic impairment, predisposition to adrenocortical insufficiency
  • Recent alcohol consumption
  • Pregnant, making plans to get pregnant or breastfeeding
  • Has taken antacid 1 hour before or 2 hours after this drug is taken

The following is a listing of side effects which can occur with Ketoconazole / Zinc Pyrithione use. These side effects are possible; however it does not arise constantly. Some of the side effects may be rare however severe. Consult your physician in case you have any of the following side effects, especially if they don’t go away:

  • Decreased platelet count
  • Bleeding
  • Inability to obtain erection
  • Blockade of synthesis of hormones from adrenal glands
  • Itching of pores and skin
  • Indigestion

Tell your physician if your situation persists or worsens.

Precautions and Interactions:

Tell your physician about all the medication, vitamins, and herbal supplements you are taking, so that you medical doctor will assist you on how to prevent or control drug interactions. Ketoconazole / Zinc Pyrithione may have interaction with the following products:

  • Alcohol
  • Alfentanil
  • Aliskiren
  • Alprazolam
  • Aluminium hydroxide and oxide
  • Amphotericin B
  • Aprepitant
  • Artesunate
  • Astemizole
  • Beclomethasone
  • Bosentan
  • Carbamazepine
  • Cimetidine
  • Cisapride
  • Corticotropin
  • Cyclosporin A
  • Dabigatran
  • Desonide
  • Didanosine
  • Docetaxel
  • Eplerenone
  • Erlotinib
  • Famotidine
  • Fexofenadine
  • Flunisolide
  • Indinavir
  • Sodium calcium edetate

If you take too much ketoconazole, call your healthcare provider or local Poison Control Center, or seek emergency medical attention right away.


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