GLYCEROL PHENYLBUTYRATE

Glycerol Phenylbutyrate is a nitrogen-binding agent that works by preventing the harmful buildup of ammonia in the body.

Uses

This medication is used for long-term management of urea cycle disorders. It may also be used for other conditions as determined by your doctor.

Warnings

Do not use Glycerol Phenylbutyrate if:

You have allergies or you are allergic to any ingredient in Glycerol Phenylbutyrate or to Sodium Phenylbutyrate
The patient is a younger than 2 months old

If any of these apply to you, contact your doctor or healthcare provider right away.

Side Effects

The most common side effects of this drug may include:

Decreased appetite
Diarrhea
Dizziness
Gas
Mild Stomach Pain or Nausea
Vomiting

Tell your doctor if the following symptoms persist or worsen.

Seek medical attention right away if any of these severe side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue; wheezing)
Confusion
Cough
Drowsiness
Fainting
Flushing
Headache
Hearing Problems
Light-Headedness
Memory Problems
New or Worsening Numbness
Tingling, or Burning of the Hands or Feet
Shortness of Breath
Taste Change
Tiredness
Weakness

Precautions

Precautions

Before using Glycerol Phenylbutyrate, tell your doctor or pharmacist if you have any medical conditions, especially of the following:

Pregnant, Planning to Become Pregnant, or are Breast-feeding
Taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
Have allergies to medicines, foods, or other substances
Have a history of nerve or nervous system problems
Have liver or kidney problems, pancreas problems, or bowel problems (eg, problems absorbing food)

Interactions

Some medicines may interact with glycerol phenylbutyrate. Tell your health care provider if you are taking any other medicines, including prescription and nonprescription, herbal or especially any of the following:

Corticosteroids (eg, prednisone), haloperidol, or valproic acid-Blood ammonia levels may be increased
Probenecid -It may increase the risk of Glycerol Phenylbutyrate’s side effects

Overdose & Brands

Call emergency hotline if someone has overdosed and has serious symptoms such as passing out or trouble breathing.

Available brand/s:

Vicol
Cofnil