GLAFENINE

Glafenine is an NSAID from the anthranilic acid derivative. Its high incidence of anaphylactic reactions led to its withdrawal from the market in most countries.

Uses

Glafenine is used in the treatment of pain and inflammation.

Warnings

Glafenine should not be given to people with the following conditions:

Peptic ulceration
Hypersensitivity to NSAIDs/aspirin
Moderate/severe renal impairment
Diabetes or hypertension
Pregnant or breastfeeding woman
Hepatitis or cardiac diseases

Side Effects

Glafenine can give rise to the following side effects:

Anaphylaxis
Hepatotoxicity
Nephrotoxicity
Gastrointestinal disturbances
Crystallization in the urinary tract
Cross-reactivity with floctafenine

Precautions

Precautions

Take precautions in patients with the following conditions:

Liver failure
Infection
Haemorrhagic disorders
Hypertension
Cardiac diseases
Asthma
Pregnancy and lactation

Interactions

Glafenine may interact with the following:

Oral anticoagulants
Antivirals
Phenytoin
Sulfonylurea antidiabetic
Methotrexate
Cardiac glycosides
ACE inhibitors
Diuretics
β-blocker
Other NSAIDs
Lithium
Ciclosporin
Tacrolimus
Moclobemide
Corticosteroids
Antiplatelet drugs
Biphosphonates
SSRIs
Pentoxifylline
Alcohol
Tobacco
Quinolones

Overdose & Brands

If you think you may have used Glafenine more than the recommended dose, seek medical help immediately.

Available Brands:

Analfan
Glafenine Alex
Glaphine
Glifanan