CLOMETHIAZOLE

This drug is known as a Chlormethiazole. Clomethiazole is a sedative and hypnotic originally developed by Hoffmann-La Roche in the 1930s.

The drug is used in treating and preventing symptoms of acute alcohol withdrawal.

No available information.

Most common side effects of this drug include:

  • Nasal Congestion And Irritation
  • Conjunctival Irritation
  • Headache

Rare side effects include:

  • Paradoxical Excitement
  • Confusion
  • Dependence
  • Gi Disturbances
  • Rash
  • Urticarial
  • Bullous Eruption
  • Anaphylaxis
  • Alterations In Liver Enzymes

Potentially fatal effect:

  • Respiratory Depression

Precautions

Before taking this medication, tell your doctor your medical history especially of:

  • Chronic Pulmonary Insufficiency
  • Cardiac And Respiratory Disease
  • Hepatic Or Renal Impairment
  • History Of Drug Abuse
  • Marked Personality Disorder

Excessive sedation may occur and drowsiness may persist the next day. Maintain airway integrity during parenteral administration. Avoid prolonged use or use in 1st and 3rd trimester of pregnancy.

 

Interactions

Clomethiazole interacts with:

  • Alcohol
  • Barbiturates
  • Antipsychotics
  • Diazoxide
  • Calcium-Channel Blockers
  • Clonidine; Disulfiram
  • Clozapine
  • Diuretics
  • Moxonidine
  • Nabilone
  • Nitrates
  • Esomeprazole And Omeprazole
  • Muscle Relaxants
  • Dopaminergics
  • Lofexidine
  • Hydralazine
  • Minoxidil And Nitroprusside
  • Antifungals
  • Angiotensin Ii-Receptor Antagonist
  • Antiepileptics
  • Β-Blockers
  • Antibacterials

Call emergency hotline if someone has overdosed and has serious symptoms such as passing out or trouble breathing.

 

Available brand:

  • Clomethiazole

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