CEFTIBUTEN

COMMON BRAND NAME(S): Cedax

GENERIC NAME(S): CEFTIBUTEN
Description: Ceftibuten inhibits bacterial cell wall synthesis. It is stable to hydrolysis by many β-lactamases and has greater activity than 1st or 2nd generation cephalosporins against gram negative bacteria. It is less active in vitro than cefexime against S. pneumoniae.

Pharmacokinetics:

Absorption: Rapidly absorbed from the GI tract after oral admin.

Distribution: 65-77% bound to plasma proteins.

Excretion: Plasma half-life: 2.0-2.3 hr; prolonged in renal impairment. Mainly in the urine and feces.

This cephalosporin antibiotic treats a wide variety of bacterial infections by stopping the growth of bacteria. This antibiotic treats only bacterial infections. It will not work for viral infections (e.g., common cold, flu).

How to use ceftibuten

Take this medication by mouth with or without food, usually once daily or as directed by your doctor.

The dosage is based on your medical condition and response to therapy.

Antibiotics work best when the amount of medicine in your body is kept at a constant level. Therefore, take this drug at evenly spaced intervals.

Continue to take this medication until the full prescribed amount is finished, even if symptoms disappear after a few days. Stopping the medication too early may result in a return of the infection.

Inform your doctor if your condition persists or worsens.

Notify your doctor or pharmacist promptly if any of these effects persist or worsen:

  • Nausea/vomiting
  • Diarrhea
  • stomach upset
  • headache

Tell your doctor immediately if any of these unlikely but serious side effects occur:

  • dark urine
  • persistent nausea/vomiting
  • yellowing eyes/skin
  • black stool
  • change in the amount of urine
  • joint pain
  • new signs of infection (e.g., fever, persistent sore throat)
  • easy bleeding/bruising
  • tiredness
  • fast/pounding heartbeat
  • seizures
  • mental/mood changes (such as confusion)

This medication may rarely cause a severe intestinal condition (Clostridium difficile-associated diarrhea) due to a type of resistant bacteria. This condition may occur during treatment or weeks to months after treatment has stopped.

Use of this medication for prolonged or repeated periods may result in oral thrush or a new vaginal yeast infection.

A very serious allergic reaction to this drug is rare.

This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.

Precautions

Consult your doctor regarding these precautions:

  • Allergic reaction to this medication.
  • Patients with medical history of kidney disease, or stomach/intestinal disease (e.g., colitis).
  • Elderly people may be at greater risk for side effects while using this drug.
  • Used only when clearly needed during pregnancy.
  • Consult your doctor before breast-feeding.

 

Interactions

Before using this medication, tell your doctor or pharmacist of all prescription and nonprescription/herbal products you may use, especially of: live bacterial vaccines.

Although most antibiotics probably do not affect hormonal birth control such as pills, patch, or ring, some antibiotics may decrease their effectiveness.

This medication may interfere with certain laboratory tests (including Coombs’ test, certain urine glucose tests), possibly causing false test results.

This document does not contain all possible interactions. Therefore, before using this product, tell your doctor or pharmacist of all the products you use. Keep a list of all your medications with you, and share the list with your doctor and pharmacist.

Overdose

If overdose is suspected, contact a poison control center or emergency room immediately. Symptoms of overdose may include seizures.

Notes

Do not share this medication with others.

This medication has been prescribed for your current condition only. Do not use it later for another infection unless told to do so by your doctor. A different medication may be necessary in that case.

Missed Dose

If you miss a dose, take it as soon as you remember. If it is near the time of the next dose, skip the missed dose and resume your usual dosing schedule. Do not double the dose to catch up.

Storage

Store between 36-77 degrees F (2-25 degrees C) away from light and moisture. Do not store in the bathroom. Keep all medicines away from children and pets.

Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company for more details about how to safely discard your product.

 

Brands:

Available Brands

Cedax [ Merck Sharp & Dohme ]

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