AVASTIN (BEVACIZUMAB) - Watsons Health

AVASTIN (BEVACIZUMAB)

This drug works by blocking a certain protein (vascular endothelial growth factor-VEGF) thereby decreasing the blood supply to the tumor and slowing tumor growth.

This medication is a man-made antibody (IgG1) used to treat kidney, cervical, ovarian, colon, and rectal cancer. Bevacizumab is also used to treat lung cancer (non-small cell type), certain types of brain tumors, and cancer found in the fallopian tube or lining of the abdominal wall (peritoneal).

Tear in the stomach/intestines (gastrointestinal perforation) is rare in this medication. It may also increase the risk of serious (possibly fatal) bleeding, such as bleeding from the stomach/intestines or in the brain. Don’t take this medication if you have any serious bleeding problems. Get medical help right away if you have any signs of these serious side effects, including bloody or black/tarry stools, persistent or severe stomach/abdominal pain, constipation with vomiting, vomit that is bloody or looks like coffee grounds, coughing up blood, shortness of breath, dizziness/fainting, unusual or persistent tiredness/weakness, severe headache, fever.

Dry mouth, cough, voice changes, loss of appetite, diarrhea, vomiting, constipation, mouth sores, nausea, or headache may occur. If any of these effects persist or worsen, notify your doctor or pharmacist right away.

Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.

Precautions

Tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies before using Bevacizumab.  This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

It’s important to discuss with your doctor or pharmacist your medical history, especially of: stomach/intestinal ulcers, bleeding problems (such as recent bloody vomiting or coughing up blood), recent major surgery, recent injuries/wounds, high blood pressure, kidney disease, diabetes.

 

Interactions

Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor’s approval.

If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call emergency hotline. Symptoms of overdose may include: severe headache.

 

Available brands:

  • Avastin
  • Bevacizumab

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