AMLODIPINE + BENAZEPRIL

Amlodipine + Benazepril is a combination drug that is composed of amlodipine and benazepril.

Amlodipine, a dihydropyridine calcium channel blocker, hinders the transmembrane flood of calcium ions into the vascular smooth muscles to resulting in peripheral blood vessel vasodilation, through this way decreasing vascular resistance and blood pressure. Furthermore, it likewise acts on the heart muscles. Benazepril, a prodrug of benazeprilat, is an ACE inhibitor, which results in diminished plasma angiotensin II, thereby lessening both vasopressor activity and aldosterone secretion.

Use this medication precisely as recommended by your physician. Follow the prescription of your doctor carefully.

The medication dose your physician has given is based on your condition, other medications or food supplements you may take, and your reaction to treatment. To diminish your risks for adverse effects, don’t increase your dosage, take it regularly, or take it as instructed by your physician. Adverse events may still happen even at usual prescription dosages.

If your physician requests you to use this drug consistently, use it regularly to get the most benefits from it. To make you remember it better, take it at a fixed time every day.

Your doctor may need to modify your dosages to ease your symptoms or if you develop adverse reactions.

If you have any inquiries with regards to information, ask your physician or pharmacist.

Uses

Amlodipine + Benazepril is used in the following conditions:

Hypertension

This medicine may be recommended for different uses. Approach your physician or pharmacist for more information.

Warnings

Do not use Amlodipine + Benazepril in people with the following conditions:

Concomitant use withaliskiren especially in patient with DM
History of angioedema
Lactation
Pregnancy
Severe renal impairment (CrCl ≤30 mL/min)

Side Effects

Amlodipine + Benazepril may have the following side effects:

Angioedema
Anxiety
Asthenia
Cough
Decreased libido
Dermatitis
Dizziness
Dry mouth
Headache
Impotence
Muscle cramps
Musculoskeletal pain
Peripheral edema
Pharyngitis
Polyuria
Tremor

Keep in mind that your physician has recommended this drug since he or she has known that the advantage to you is more noteworthy than the risk of adverse reactions. Many individuals utilizing this medicine don’t have serious side effects.

A serious allergy to this medication is uncommon. In any case, seek emergency medical help if you see any manifestations of a serious allergic response, including a rash, tingling or swelling particularly of the face or tongue or throat, dizziness or difficulty in breathing.

This is is not a complete list of side effects. If you see other effects not recorded above, contact your physician or pharmacist.

Precautions

Take extra caution in patients with the following medical conditions:

Aortic/mitral stenosis
Congestive heart failure withor without renal insufficiency
Collagen vascular disease
Diabetes mellitus
Elderly
Hepatic and severe renal impairment
Heart attack
Obstructive hypertrophic cardiomyopathy
Patient undergoing surgery or during anesthesia
Patient withsevere obstructive coronary artery disease
Severe heart failure
Volume and salt depletion

Prior to taking this medicine, tell your physician or pharmacist if you are allergic to it, or if you have some other hypersensitivities. This drug may contain inert ingredients which can cause unfavorable side effects or different issues. Talk with your pharmacist for more information.

Interactions

Amlodipine + Benazepril may interact with the following medicines:

Aliskiren
CYP3A4 inhibitors
Everolimus
Potassiumsupplements
NSAIDs
Simvastatin
Sirolimus
Temsirolimus

Inform your physician about the drugs you take including over-the-counter medications, prescribed drugs, supplements and vitamins.

This is not a complete list of drug interactions. Approach your physician or pharmacist for more details.

The effects of certain medications can change if you consume different medications or herbal products simultaneously. This can build your risk for side effects or may cause your drugs not to work effectively. These interactions are conceivable, yet don’t generally happen. Your physician or pharmacist can prevent or oversee interactions by changing how you utilize your prescriptions or by close checking.

While utilizing this drug, don’t start, stop, or change the dose of other medicines you are using without your physician’s advice.

Overdose & Brands

If you think you have used Amlodipine + Benazepril more than the usual dosage, please seek medical help immediately.

Available Brands:

Lotrel
Amlobenz
Lotensin