Letrozole is a drug that is known as a non-steroidal aromatase protein inhibitor. It aggressively binds to the haem of the CYP enzyme to block the transformation of androstenedione and testosterone into estriol and oestradiol individually, hence, leading to decreased serum estrogen levels.
Letrozole is used in the treatment of early breast cancer In hormone receptor positive postmenopausal women.
Letrozole should not be given to women with the following conditions:
Letrozole may have the following side effects:
Take extra caution in patients with the following medical conditions:
Interactions
Letrozole may interact with the following medicines:
If there is overdose and if the victim has lost conciousness or had other signs and symptoms, seek medical help immediately.
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