Except at larger dosages, metoprolol competes for 1- receptors and has little to no impact on 2- receptors. It has no intrinsic sympathomimetic or membrane-stabilizing properties. The thiazide diuretic hydrochlorothiazide inhibits sodium reabsorption in the distal tubules, resulting in increased sodium, water, potassium, and hydrogen ions excretion.
Use this medication precisely as recommended by your physician. Follow the prescription of your doctor carefully.
The medication dose given by your physician is based on your health conditions, other medications or food supplements taken, and your reaction to the treatment. To diminish risks for adverse effects, do not increase your dosage, thus take it regularly, or take it as instructed by your physician. Adverse events may still happen even at usual prescription dosages.
If your physician requests you to use this drug consistently, take it regularly to get the most benefits from it. To make you remember it better, take it at a fixed time every day.
Your doctor may need to modify your dosages to ease your symptoms or if you develop adverse reactions.