CLIVAL CHORDOMA

CLIVAL CHORDOMA

Tumors that develop anywhere along the craniospinal axis are called chordomas. This type of tumor may often present as a hard challenge when it comes to diagnosis and treatment due to a high chance of recurrence, even after several surgeries.

Clival chordomas are types of invasive tumors that develop in the base of the skull.  This tumor is often treated with safe surgical removal and accompanied by focused radiotherapy. An individual who suffers from chordoma is still considered lucky because some types of clival chordomas can be removed through the nose using an endonasal endoscopic

TYPES 

There are three types of chordoma:

  • Conventional chordoma are the slow-growing types of tumors
  • The chondroid chordomadevelops particularly at the upper and lower ends of the vertebral column
  • The dedifferentiated chordoma is a rare and aggressive type of tumor in which a certain area transforms to a high-grade lesion, typically fibrous histiocytoma, fibrosarcoma, and rarely, osteosarcoma or rhabdomyosarcoma.

 

SYMPTOMS

Here are some common symptoms of a clival chordoma:

  • Double vision
  • Visual loss
  • Loss sense of hearing
  • Difficulty in swallowing
  • Facial numbness
  • Loss of voluntary control
  • Muscle weakness
  • Nasal congestion

DIAGNOSIS

Your doctor will be able to diagnose a clival chordoma by performing  MRI and CT scans that will clearly show the extent of tumor and bony destruction in the skull. A focus MRI of the pituitary region, temporal bones, sinuses, or the internal auditory canals is important to come out with better details of a chordoma.

 

TREATMENT

Medical treatment

A tyrosine kinase inhibitor known as imatinib is recently approved as monotherapy for those with chronic myelogenous leukemia. It is also used to dissolve tumors caused by a chordoma.

  • Surgery is one of the most recommended treatment for clival chordoma which aim to achieve the highest total resection of the tumor.

l Radiation treatment, in combination with aggressive surgical resection, is the best-suggested treatment for chordoma.

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