ALLERGIC CASCADE - Overview, Facts, Types, Symptoms and Diagnosis

ALLERGIC CASCADE

Allergic cascade describes the chain of events that occur in the human body in exposure to allergens. The asthmatic reaction involves a number of white cell and cellular structures. Moreover, the main characteristics of the inflammatory response vary from mild redness and irritation to severe anaphylaxis. To reduce or cure allergic reactions, allergen prevention and medicines are employed.

SYMPTOMS

  • Early Phase. Exposure causes rapid diffusion of the inflammatory mediators that produce the different allergic reactions. The “early phase” of an immune disease is referred to as this. It may happen seconds or minutes after being exposed to an allergen. This is also called an acute hypersensitive response, and in this instance, the allergen is ragweed pollen.
  • Late Phase. The late phase occurs four to six hours during the first encounter. The entrance of additional cells, such as eosinophils, neutrophils, and lymphocytes, causes tissue redness and inflammation in the later phase response. Cell types and eosinophils produce cytokines, which function as small signals, directing all these cells of the body of disease. Further, cytokines are produced by TH2 lymphocytes, attracting much more of these inflammatory cells.

DIAGNOSIS

When a bee bites you, do you flare out in rashes? Or do you experience sneezing whenever you touch a dog? If this is the case, you may already be aware of some of your sensitivities. However, you may not always be mindful of what is triggering your allergy symptoms. Therefore, make an appointment with your doctor to get a proper diagnosis of your condition.

Usually, your doctor will identify allergic cascade based on your medical history, physical exam, and allergy tests. These tests include:

  • SPT or skin prick test
  • Intradermal skin test
  • Blood test
  • Patch test

TREATMENT

The most fundamental and effective method to treating allergies is to prevent the chemicals that cause them, known as allergens. Most allergies, such as animal dander, foods, and medicines, may be avoided quite easily.

Antihistamines. The ability of allergens (medically known as H1 receptor blockers) to avoid specific allergy reactions. They help to relieve itchiness, asthma, and colds.

Shots for allergies. To immunize a patient by administering escalating doses of the irritants to which the subject is sensitive. The immune system grows less responsive to certain irritants over time, producing less IgE in reaction, and becoming more forgiving upon re-exposure to them.

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