Precautions
Take extra caution in patients with the following medical conditions:
- Bipolar disorder
- Anemia
- Liver disease
- Pregnancy or those with potential for vitamin deficiencies due to other illnesses or eating habits
- At risk for suicide and other serious events
- Transient or worsening anxiety
- Concomitant use of SSRIs, TCAs, clomipramine and herbal supplements containing tryptophan
- Kidney impairment
- Pregnancy
- Lactation
- Children
- Elderly greater or equal to 65 years of age
Interactions
Ademetionine may interact with the following medicines:
- Clomipramine
- Selective serotonin reuptake inhibitors (SSRI)
- Tricyclic antidepressants like clomipramine
- Over-the-counter and herbal supplements containing tryptophan