ATROPINE SULFATE - Uses, Warnings, Side Effects, Precautions, Overdose and Brands


Atropine sulfate belongs to a class of drugs called antimuscarinic drugs. Atropine injection is administered before anesthesia to diminish mucus discharges like salivation. Atropine is also utilized to help keep the heart beating normally. Atropine sulfate is likewise used to reverse the effects brought about by certain drugs and various pesticides.

Atropine is an anticholinergic drug that hinders the reactions of the sphincter muscle of the iris and the accommodative muscle of the ciliary body in the eye to cholinergic stimulation, further leading to eye dilatation and paralysis of accommodation.

Atropine sulfate is used in the following:

  • For mydriasis and/or cycloplegia of the eye
  • Cycloplegic refraction of the eye
  • Pupillary dilation of the eye

Do not give atropine to people with the following conditions:

  • Hypersensitivity
  • Patients with known or suspected angle-closure glaucoma
  • Children below three years old
  • Children with Down’s syndrome, spastic paralysis or brain damage

Atropine sulfate may have the following side effects:

  • Irritation
  • Follicular conjunctivitis
  • Vascular congestion
  • Edema
  • Exudates
  • Eczematoid dermatitis
  • Hypotension

Take extra caution in patients with the following medical conditions:

  • Pregnancy
  • Lactation
  • Fertility



Atropine sulfate may interact with the following medicines:

  • Antimuscarinic drugs
  • Amantadine
  • Antihistamines
  • Phenothiazine
  • Antipsychotics

Tricyclic antidepressants

Overdose may bring about the following symptoms:

  • Flushing
  • Dryness of the skin
  • Blurred vision
  • A rapid and irregular pulse
  • Fever
  • Abdominal distension in infants
  • Convulsions and hallucinations
  • Loss of neuromuscular coordination
  • Coma
  • Respiratory failure

Seek medical help immediately.

Available Brands:

  • Atropan
  • Atroptal
  • Isopto
  • Phil Pharmawealth
  • Anespin
  • Euro-Med

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