HUMAN PAPILLOMAVIRUS 9-VALENT VACCINE

CHLORAMPHENICOL

Chloramphenicol is an antibiotic that is used to treat various infections. It represses the creation of bacterial protein by binding to the 50s subunit of the bacterial ribosome. This further prevents peptide bond creation by peptidyl transferase. It has both bacteriostatic and bactericidal activities against the bacteria H. influenzae, N. meningitis, and S. pneumoniae. Chloramphenicol is a broad spectrum antibiotic.

Uses

Chloramphenicol is used to treat the following:

  • Eye infections
  • Bacterial meningitis
  • Anaerobic bacterial infections
  • Anthrax
  • Brain abscess
  • Ehrlichiosis
  • Gas gangrene
  • Granuloma inguinale
  • Infections caused by H. influenzae
  • Listeriosis
  • Plague
  • Psittacosis
  • Q fever
  • Severe gastroenteritis
  • Severe melioidosis
  • Severe systemic infections with Camphylobacter fetus
  • Tularaemia
  • Whipple’s disease

Warnings

Do not use chloramphenicol in people with the following conditions:

  • History of hypersensitivity or toxic reaction to the drug
  • Pregnancy
  • Lactation
  • Preexisting bone marrow depression
  • Blood dyscrasias

Side Effects

Chloramphenicol may have the following side effects:

  • Bleeding
  • Peripheral and optic neuritis
  • Visual impairment
  • Blindness
  • Encephalopathy
  • Delirium
  • Mental depression
  • Aplastic anemia
  • Neutropenia
  • Thrombocytopenia
  • Grey baby syndrome

Precautions

Take extra caution in patients with the following medical conditions:

  • Impaired renal or hepatic function
  • Premature and full-term neonates

 

Interactions

Chloramphenicol may interact with the following medicines:

  • Vitamin B12
  • Phenobarbitone
  • Rifampin
  • Oral contraceptives.
  • Oral hypoglycaemic agents
  • Phenytoin

Overdose & Brands

Symptoms of overdose include the following:

  • Fever
  • Chills
  • Change in color of sputum
  • Pain with passing urine
  • Mouth sores, or wound that will not heal
  • Throwing up blood
  • Black, red, or tarry stools
  • Bleeding from the gums
  • Very bad dizziness or passing out
  • Feeling very tired or weak
  • Feeling confused
  • Mood changes
  • Change in eyesight

Seek medical help immediately.

Available Brands:

  • Alphagram
  • Boie Chlor
  • Chlorocair
  • Chloro-S
  • Chloro-V

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