Cefuroxime is an enteral second-generation cephalosporin antibiotic. It was discovered by Glaxo (now GlaxoSmithKline) and first marketed in 1978 as Zinacef. It received approval from the U.S. Food and Drug Administration in October 1983.
Cefuroxime is an enteral second-generation cephalosporin antibiotic. It was discovered by Glaxo (now GlaxoSmithKline) and first marketed in 1978 as Zinacef. It received approval from the U.S. Food and Drug Administration in October 1983.
Lower and upper respiratory tract, genito-urinary tract, skin and soft tissue infections; gonorrhea including acute uncomplicated gonococcal urethritis and cervicitis. Early and late Lyme disease in adults and children older than 12 years.
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Nausea, vomiting, diarrhea, or stomach pain may occur. Dizziness and drowsiness may occur less frequently, especially with higher doses. If any of these effects persist or worsen, notify your doctor or pharmacist promptly.
Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.
Tell your doctor right away if any of these unlikely but serious side effects occur: unusual tiredness/weakness.
Tell your doctor right away if any of these rare but very serious side effects occur: yellowing of the eyes/skin, severe stomach/abdominal pain, persistent nausea/vomiting, dark urine, signs of kidney problems (such as change in the amount of urine), signs of new infection (e.g., fever, persistent sore throat), easy bruising/bleeding, jerky movements, chest pain, mental/mood changes (such as confusion).
This medication may rarely cause a severe intestinal condition (Clostridium difficile-associated diarrhea) due to a resistant bacteria. This condition may occur while receiving therapy or even weeks to months after treatment has stopped. Do not use anti-diarrhea products or narcotic pain medications if you have the following symptoms because these products may make them worse. Tell your doctor right away if you develop: persistent diarrhea, abdominal or stomach pain/cramping, blood/mucus in your stool.
Use of this medication for prolonged or repeated periods may result in oral thrush or a new vaginal yeast infection (oral or vaginal fungal infection). Contact your doctor if you notice white patches in your mouth, a change in vaginal discharge or other new symptoms.
A very serious allergic reaction to this drug is unlikely, but seek immediate medical attention if it occurs. Symptoms of a serious allergic reaction may include: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.
This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.
Precautions
Before taking cefuroxime, tell your doctor or pharmacist if you are allergic to it; or to penicillins or other cephalosporin antibiotics (e.g., cephalexin); or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.
Before using this medication, tell your doctor or pharmacist your medical history, especially of: kidney disease, intestinal disease (colitis), liver disease, poor nutrition.
This drug may make you dizzy or drowsy. Do not drive, use machinery, or do any activity that requires alertness until you are sure you can perform such activities safely. Limit alcoholic beverages.
Caution is advised when using this drug in the elderly because they may be more sensitive to its effects.
This medication should be used only when clearly needed during pregnancy. Discuss the risk and benefits with your doctor.
This medication passes into breast milk. Consult your doctor before breast-feeding.
Interactions
Your healthcare professionals (e.g., doctor or pharmacist) may already be aware of any possible drug interactions and may be monitoring you for it. Do not start, stop, or change the dosage of any medicine before checking with them first.
Before using this medication, tell your doctor or pharmacist of all prescription and nonprescription/herbal products you may use, especially of: “blood thinners” (e.g., warfarin), live bacterial vaccines.
Although most antibiotics are unlikely to affect hormonal birth control such as pills, patch, or ring, a few antibiotics (such as rifampin, rifabutin) can decrease their effectiveness. This could result in pregnancy. If you use hormonal birth control, ask your doctor or pharmacist for more details.
This medication may affect the results of certain lab tests. It may cause false positive results with certain diabetic urine testing products (cupric sulfate-type) and false negative results with certain blood glucose tests. Make sure laboratory personnel and your doctors know you use this drug.
This document does not contain all possible interactions. Therefore, before using this product, tell your doctor or pharmacist of all the products you use. Keep a list of all your medications with you, and share the list with your doctor and pharmacist.
Symptoms of overdose may include convulsions. If overdose is suspected, bring the victim to the nearest hospital right away.
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