Weir-Mitchell disease is a rare disease that affects the feet and occasionally the hands. It is believed to trigger extreme burning pain, intense redness, and a rise in skin temperature that can be episodic or persistent.
Heat, pressure, moderate exercise, effort, sleeplessness, or stress are frequent triggers for the attacks, which occur on a regular basis. Further, the Weir-Mitchell Disease was the first human disorder in 2004. It can be a primary or subsequent symptom of another illness.
Moreover, when its relationship to the SCN9A gene was described in the Journal of Medical Genetics, it was conceivable to correlate an ion channel mutation with persistent neuropathic pain.