VALSAR PLUS

Do not use Valsar Plus in people with the following conditions:

• Hypersensitivity
• Pregnancy: Amlodipine and valsartan are contraindicated during pregnancy. They can potentially harm the developing fetus and may cause fetal harm or death. If you are pregnant or planning to become pregnant, it is important to discuss alternative treatment options with your healthcare provider.
• Severe liver disease: Amlodipine and valsartan should be used with caution or avoided in patients with severe liver disease. Both medications are metabolized by the liver, and impaired liver function can affect their clearance from the body. Your healthcare provider will determine if the benefits outweigh the risks in your specific situation.
• Severe kidney disease: Amlodipine and valsartan may not be recommended in patients with severe kidney disease or end-stage renal disease (ESRD). These medications can affect kidney function, and their use should be carefully evaluated by a healthcare provider.
• Hypotension: Amlodipine and valsartan can cause low blood pressure (hypotension) as a side effect. If you already have low blood pressure or are prone to hypotension, their use should be monitored closely by a healthcare provider.

It is important to discuss your medical history, including any pre-existing conditions or allergies, with your healthcare provider before starting amlodipine and valsartan. They will be able to assess your specific situation and determine if these medications are appropriate for you.

Remember, this is not an exhaustive list of contraindications. Always consult with your healthcare provider for personalized advice based on your specific medical condition and medication profile.

Valsar Plus may have the following side effects:

• Swelling in the ankles, feet, or hands (edema)
• Flushing or feeling warm
• Dizziness or lightheadedness
• Fatigue or tiredness
• Headache
• Nausea or stomach discomfort
• Muscle cramps or weakness
• Diarrhea
• Back pain
• Low blood pressure (hypotension)

It is important to note that these side effects are usually mild and temporary. Most people tolerate amlodipine and valsartan well. However, if you experience any persistent or severe side effects, it is important to contact your healthcare provider for further evaluation.

In rare cases, amlodipine and valsartan can cause more serious side effects that require immediate medical attention. These may include:

• Allergic reactions, such as rash, itching, swelling, severe dizziness, or difficulty breathing
• Liver problems, including yellowing of the skin or eyes, dark urine, or persistent nausea/vomiting
• Kidney problems, such as decreased urine output, swelling in the legs or feet, or unexplained weight gain
• Chest pain or rapid heartbeat

If you experience any of these severe side effects, seek medical help right away.

Keep in mind that your physician has recommended this drug since he or she has known that the advantage to you is more noteworthy than the risk of adverse reactions. Many individuals utilizing this medicine don’t have serious side effects.

This is not a complete list of side effects. If you see other effects not recorded above, contact your physician or pharmacist.

Precautions

Take extra caution in patients with the following medical conditions:

• Pre-existing conditions, allergies, or previous adverse reactions to medications
• Alcohol consumption: Alcohol can potentiate the blood pressure-lowering effects of amlodipine and valsartan. It is advisable to limit or avoid alcohol consumption while taking these medications

Prior to taking this medicine, tell your physician or pharmacist if you are allergic to it, or if you have some other hypersensitivities. This drug may contain inert ingredients which can cause unfavorable side effects or different issues. Talk with your pharmacist for more information.

Interactions

Valsar Plus may interact with the following medicines:

• Other blood pressure medications: Combining amlodipine and valsartan with other blood pressure medications, such as beta blockers or diuretics, may enhance the blood pressure-lowering effects. Your healthcare provider will carefully monitor your blood pressure and adjust your medications as needed.
• Potassium supplements or potassium-sparing diuretics: Amlodipine and valsartan can cause an increase in potassium levels in the blood.
• Taking potassium supplements or potassium-sparing diuretics, such as spironolactone, while on amlodipine and valsartan may further increase potassium levels. Regular monitoring of potassium levels is important to avoid potentially dangerous levels.
• Nonsteroidal anti-inflammatory drugs (NSAIDs): NSAIDs, such as ibuprofen or naproxen, may reduce the effectiveness of amlodipine and valsartan in lowering blood pressure. They can also increase the risk of kidney problems. It is advisable to consult your healthcare provider before taking NSAIDs while on amlodipine and valsartan.
• Grapefruit juice: Grapefruit juice can interfere with the breakdown of amlodipine in the body, leading to increased levels of the medication.
• This can potentially increase the risk of side effects. It is generally recommended to avoid consuming grapefruit or grapefruit juice while taking amlodipine and valsartan.
• CYP3A4 inhibitors and inducers: Amlodipine is primarily metabolized by the CYP3A4 enzyme in the liver. Medications that inhibit or induce this enzyme can affect the levels of amlodipine in the body. It is important to inform your healthcare provider about any medications you are taking that may interact with CYP3A4.
• Herbal supplements: Certain herbal supplements, such as St. John’s wort, may interact with amlodipine and valsartan. It is important to discuss the use of any herbal supplements with your healthcare provider to avoid potential interactions.

Inform your physician about the drugs you take including over-the-counter medications, prescribed drugs, supplements and vitamins.

This is not a complete list of drug interactions. Approach your physician or pharmacist for more details.

The effects of certain medications can change if you consume different medications or herbal products simultaneously. This can build your risk for side effects or may cause your drugs not to work effectively. These interactions are conceivable, yet don’t generally happen. Your physician or pharmacist can prevent or oversee interactions by changing how you utilize your prescriptions or by close checking.

While utilizing this drug, don’t start, stop, or change the dose of other medicines you are using without your physician’s advice.

If you suspect an overdose, contact your doctor right away.

Available Brands:

• Valsar Plus