TUBERCULOSIS

Tuberculosis (TB) is an infection caused by slow-growing bacteria that grow best in areas of the body that have lots of blood and oxygen, like the lungs. This is called pulmonary TB. But TB can also spread to other parts of the body, which is called extrapulmonary TB. Treatment usually takes about 6 to 9 months to treat TB, but some TB infections need to be treated for up to 2 years.

Pulmonary TB (in the lungs) is contagious. It spreads when a person who has active TB breathes out air that has the TB bacteria in it and then another person breathes in the bacteria from the air. An infected person releases even more bacteria when he or she does things like cough or laugh.

If TB is only in other parts of the body (extrapulmonary TB), it does not spread easily to others.

Some people are more likely than others to get TB. This includes people who:

  • Have HIV or another illness that weakens the immune system.
  • Have close contact with someone who has active TB, such as living in the same house as someone who is infected with TB.
  • Care for a patient who has active TB, such as doctors or nurses.
  • Live or work in crowded places, such as prisons, nursing homes, or homeless shelters, where other people may have active TB.
  • Have poor access to health care, such as homeless people and migrant farm workers.
  • Abuse drugs or alcohol.
  • Travel to or were born in places where untreated TB is common, such as Latin America, Africa, Asia, Eastern Europe, and Russia.

It is important for people who are at a high risk for getting TB to get tested once or twice every year.

Tuberculosis is either latent or active.

  • Latent TB means that you have the TB bacteria in your body, but your body’s defenses (immune system) are keeping it from turning into active TB. This means that you don’t have any symptoms of TB right now and can’t spread the disease to others. If you have latent TB, it can become active TB.
  • Active TB means that the TB bacteria are growing and causing symptoms. If your lungs are infected with active TB, it is easy to spread the disease to others.

Symptoms of active TB in the lungs

Symptoms of active TB in the lungs begin gradually and develop over a period of weeks or months. You may have one or two mild symptoms and not even know that you have the disease.

Common symptoms include:

  • A cough with thick, cloudy, and sometimes bloody mucus from the lungs (sputum) for more than 2 weeks.
  • Fever, chills, and night sweats.
  • Fatigue and weakness.
  • Loss of appetite and unexplained weight loss.
  • Shortness of breath and chest pain.

Symptoms of an active TB infection outside the lungs

Symptoms of TB outside the lungs (extrapulmonary TB) differ widely because of which area of the body is infected. For example, back pain can be a symptom of TB in the spine, or your neck may get swollen when lymph nodes in the neck are infected.

DIAGNOSIS

Diagnosing active TB in the lungs

Doctors diagnose active tuberculosis (TB) in the lungs (pulmonary TB) by using a medical history and physical exam, and by checking your symptoms (such as an ongoing cough, fatigue, fever, or night sweats). Doctors will also look at the results of a:

  • Sputum culture.
  • Sputum cytology.
  • Chest X-ray.
  • Rapid sputum test.

Diagnosing latent TB in the lungs

A tuberculin skin test will show if you have ever had a TB infection.

Diagnosing TB outside the lungs

Diagnosing TB in other parts of the body (extrapulmonary TB) requires more testing. Tests include:

  • Biopsy of the affected area.
  • Urine culture for TB in the kidneys.
  • Lumbar puncture for TB meningitis.
  • CT scan for TB that has spread throughout the body (miliary TB) and to detect lung cavities caused by TB.
  • This test looks for TB in the brain or the spine.

 

RECOMMENDED MEDICATIONS

Active tuberculosis (TB)

Several antibiotics are used at the same time to treat active tuberculosis (TB) disease. For people who have multidrug-resistant TB, treatment may continue for as long as 24 months. These antibiotics are given as pills or injections.

For active TB, there are different treatment recommendations for children, pregnant women, people who have HIV and TB, and people who have drug-resistant TB.

Extrapulmonary TB

This is treated with the same medicines and for the same length of time as active TB in the lungs (pulmonary TB). But TB throughout the body (miliary TB) or TB that affects the brain or the bones and joints in children may be treated for at least 12 months.

Corticosteroid medicines also may be given in some severe cases to reduce inflammation.

Latent TB

One antibiotic usually is used to treat latent TB infection, which cannot be spread to others but can develop into active TB disease. The antibiotic usually is taken for 4 to 9 months. 1 Or more than one antibiotic may be taken once a week for 12 weeks. 5 For this treatment, a health professional watches you take each dose of antibiotics. Taking every dose of antibiotic helps prevent the TB bacteria from getting resistant to the antibiotics.

Related Articles

TETRALOGY OF FALLOT

Overview and FactsTypes and SymptomsDiagnosis & MedicationsOverview and Facts Tetralogy of Fallot is a congenital heart defect that affects the [...]

TRICHINOSIS

Overview and FactsTypes and SymptomsDiagnosis & MedicationsOverview and Facts Trichinosis, also known as trichinellosis, is a parasitic infection caused by [...]

TRIGEMINAL NEURALGIA

Overview and FactsTypes and SymptomsDiagnosis & MedicationsOverview and Facts Trigeminal neuralgia is a neurological condition characterized by severe facial pain. [...]