Description: Tacrolimus is an immunosuppressant that inhibits T-lymphocyte activation.
Description: Tacrolimus is an immunosuppressant that inhibits T-lymphocyte activation.
Tacrolimus is assigned to Pregnancy Category C.
This drug is associated with premature delivery risk, neonatal hyperkalemia, and renal dysfunction. Animal studies revealed maternal toxicity, and decreases in pup weight, viability, and live births, and increases in abortions, late resorptions, fetal death in utero, fetal malformations, and developmental variations.
Tacrolimus Breastfeeding Warning
Tacrolimus is excreted into breastmilk and must be discontinued when breastfeeding.
Other side effects include:
Precautions
Drug Interactions
Live virus vaccines and other immunosuppressants should be avoided while receiving tacrolimus.
Dosing
Starting dose: 0.075 mg/kg/day to 0.2 mg/kg/day; taken twice daily.
Taken with food to reduce abdominal pain; but food also reduces its absorption.
Storage: Room temperature between 15 C – 30 C (59 F – 86 F).
Brands
Available Brands
Lesinurad suppresses the enzymes uric acid transporter 1 (URAT1) and organic anion carrier 4 (OAT4), which increases uric acid outflow [...]
Lemborexant is an orexin potent inhibitor that's competitive. It is considered to prevent the attachment of wake-promoting neurotrophins orexin A [...]
Insulin lispro is a fast-acting human insulin alternative, whereas insulin lispro protamine is a slow-acting human insulin alternative. They both [...]
