SULINDAC

Do not use this drug:

• If you are allergic to any ingredient in Sulindac
• If you have had a severe allergic reaction to Aspirin or an NSAID (eg, Ibuprofen, Celecoxib)
• Before or after having a bypass heart surgery
• Together with another NSAID (eg, ibuprofen)
• If you are in the last 3 months of pregnancy

Common side effects may include:

• Ulcerations of the Stomach and Small Intestine
• Abdominal Pain
• Cramping
• Nausea
• Gastritis
• Serious Gastrointestinal Bleeding
• Liver Toxicity

Notify your doctor promptly if any of these symptoms persist or worsen.

Your doctor may have prescribed this medication because he or she judged that the benefit to you is greater than the risk of side effects.

Serious side effects may include:

• Black Tarry Stools
• Weakness
• Dizziness Upon Standing (Orthostatic Hypotension)
• Severe Allergic Reaction
• Kidney Impairment
• Ringing in the Ears

Seek immediate medical attention if you experience any of these serious side effects.

Precautions

Before taking this drug, tell your doctor or pharmacist:

• If you are allergic to it or to Aspirin or other NSAID; or if you have any other allergies.
• If you are pregnant or breastfeeding.
• Your medical condition or history, especially of:
  • Asthma (Including a History of Worsening Breathing after Taking Aspirin or other Nsaids)
  • Bleeding or Clotting Problems
  • Growths in the Nose (Nasal Polyps)
  • Heart Disease (such as Previous Heart Attack)
  • High Blood Pressure
  • Kidney Stones
  • Liver Disease
  • Stomach or Intestinal or Esophagus Problems (such as Bleeding, Ulcers, Recurring Heartburn)
  • Stroke

Interactions

Drug interactions may either lessen the effectiveness of this drug or heighten the risk for severe side effects. It’s important to inform your doctor all the medication including prescription and non-prescription and herbal medicines you are taking or going to take.

Possible interactions with this drug are:

• Bisphosphonates (eg, Alendronate, Risedronate)
• Anticoagulants (eg, Warfarin)
• Aspirin
• Corticosteroids (eg, Prednisone)
• Heparine
• Other Nsaids (eg, Ibuprofen)
• Selective Serotonin Reuptake Inhibitors (SSRIs) (eg, Fluoxetine)
• Probenecid
• Diflunisal
• Dimethyl Sulfoxide (DMSO)
• Cyclosporine
• Lithium
• Methotrexate
• Quinolones (eg, Ciprofloxacin)
• Sulfonylureas (eg, Glipizide)
• Angiotensin-Converting Enzyme (ACE) Inhibitors (eg, Enalapril)
• Angiotensin Receptor Blockers (eg, Losartan)

Diuretics (eg, Furosemide, Hydrochlorothiazide)

Call emergency hotline if someone has overdosed and has serious symptoms such as passing out or trouble breathing.

Symptoms of overdose may include:

• Severe Stomach Pain
• Vomit that Looks Like Coffee Grounds
• Extreme Drowsiness
• Loss of Consciousness
• Slowed or Shallow Breathing

Available brand/s:

• Sulindac