COMMON BRAND NAME(S): None
GENERIC NAME(S): RIBOFLAVIN
Description: Riboflavin (vitamin B2) is a naturally occuring substance necessary for many processes in the body. It is importanct in the maintenance of many tissues in the body.
Pharmacokinetics:
Absorption: Readily absorbed from the upper GI tract.
Distribution: Widely distributed, including erythrocytes and liver. Crosses the placenta and enters breast milk.
Excretion: About 9% excreted in urine as unchanged drug.
Effective for:
Possibly Effective for:
Pregnancy Risk: Category C (Risk cannot be ruled out)
Riboflavin is LIKELY SAFE for most people when taken by mouth. In some people, riboflavin can cause the urine to turn a yellow-orange color. When taken in high doses, riboflavin might cause diarrhea, an increase in urine, and other side effects.
Special Precautions & Warnings:
Pregnancy and breast-feeding: Riboflavin is LIKELY SAFE for pregnant or breast-feeding women when taken in the amounts recommended. The recommended amounts are 1.4 mg per day for pregnant women and 1.6 mg per day in breast-feeding women. Riboflavin is POSSIBLY SAFE when taken by mouth in larger doses, short-term. Some research shows that riboflavin is safe when taken at a dose of 15 mg once every 2 weeks for 10 weeks.
Hepatitis, Cirrhosis, Billary obstruction: Riboflavin absorption is decreased in people with these conditions.
Minor Interaction: Be watchful with this combination
Drying medications (Anticholinergic drugs) interacts with RIBOFLAVIN
Some drying medications can affect the stomach and intestines. Taking these drying medications with riboflavin (vitamin B2) can increase the amount of riboflavin that is absorbed in the body. But it’s not known if this interaction is important.
Medications for depression (Tricyclic antidepressants) interacts with RIBOFLAVIN
Some medications for depression can decrease the amount of riboflavin in the body. This interaction is not a big concern because it only occurs with very large amounts of some medications for depression.
Phenobarbital (Luminal) interacts with RIBOFLAVIN
Riboflavin is broken down by the body. Phenobarbital might increase how quickly riboflavin is broken down in the body. It is not clear if this interaction is significant.
Probenecid (Benemid) interacts with RIBOFLAVIN
Probenecid (Benemid) can increase how much riboflavin is in the body. This might cause there to be too much riboflavin in the body. But it’s not known if this interaction is a big concern.
Dosing:
The following doses have been studied in scientific research:
BY MOUTH:
For treating low levels of riboflavin (riboflavin deficiency) in adults: 5-30 mg of riboflavin (Vitamin B2) daily in divided doses.
For preventing migraine headaches: 400 mg of riboflavin (Vitamin B2) per day. It may take up to three months to get best results.
For preventing cataracts: a daily dietary intake of approximately 2.6 mg of riboflavin (Vitamin B2) has been used. A combination of 3 mg of riboflavin (Vitamin B2) plus 40 mg of niacin daily has also been used.
The daily recommended dietary allowances (RDAs) of riboflavin (Vitamin B2) are: Infants 0-6 months, 0.3 mg; infants 7-12 months, 0.4 mg; children 1-3 years, 0.5 mg; children 4-8 years, 0.6 mg; children 9-13 years, 0.9 mg; men 14 years or older, 1.3 mg; women 14-18 years, 1 mg; women over 18 years, 1.1 mg; pregnant women, 1.4 mg; and breastfeeding women, 1.6 mg.
Brands:
There are no brands containing this molecule.
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