QUINAGOLIDE - Watsons Health

QUINAGOLIDE

Quinagolide is a drug that is known as a non-ergot derivative. It selectively binds to dopamine D2-receptors to stop the secretion of the hormone prolactin from the anterior pituitary gland. It does not decrease or affect the other levels of pituitary hormones.

Quinagolide is used for hyperprolactinemia originating from a prolactin-secreting pituitary tumor or other causes.

Quinagolide should not be given to those with liver and kidney problems.

Quinagolide may give rise to the following side effects:

  • Headache
  • Dizziness
  • Nausea
  • Vomiting
  • Diarrhoea
  • Abdominal pain/discomfort
  • Constipation
  • Dyspepsia
  • Nasal congestion
  • Flushing
  • Weight gain
  • Muscle weakness
  • Extremity pain
  • Breast pain
  • Anorexia
  • Insomnia
  • Fatigue
  • Mood liability
  • Somnolence
  • Acute psychosis
  • Edema
  • Hypotension
  • Syncope
  • Neutropenia
  • Increased bilirubin
  • Increased CPK
  • Decreased haematocrit
  • Decreased haemoglobin
  • Increased potassium
  • Increased transaminases
  • Increased triglycerides

Precautions

Extra caution should be taken by women of childbearing age, as it may restore fertility. It should not be given during pregnancy or during breastfeeding. This should not be given to people who will be operating machinery or those who will operate machines.

Take precautions in people with the following conditions:

  • History of psychotic disorders
  • Patients treated with dopamine agonists for Parkinson’s disease such as Quinagolide especially at high doses
  • Elderly
  • Kidney problems
  • Liver problems

 

Interactions

Quinagolide may interact with the following medicines:

  • Metoclopramide
  • Antipsychotic drugs that have dopamine antagonistic action

Symptoms of Quinagolide may include the following:

  • Dizziness
  • Drowsiness
  • Headache
  • Severe nausea
  • Vomiting
  • Hallucinations
  • Hypotension
  • Collapse

 

Available Brand/s:

Norprolac

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