QUINAGOLIDE

Quinagolide is a drug that is known as a non-ergot derivative. It selectively binds to dopamine D2-receptors to stop the secretion of the hormone prolactin from the anterior pituitary gland. It does not decrease or affect the other levels of pituitary hormones.

Uses

Quinagolide is used for hyperprolactinemia originating from a prolactin-secreting pituitary tumor or other causes.

Warnings

Quinagolide should not be given to those with liver and kidney problems.

Side Effects

Quinagolide may give rise to the following side effects:

Headache
Dizziness
Nausea
Vomiting
Diarrhoea
Abdominal pain/discomfort
Constipation
Dyspepsia
Nasal congestion
Flushing
Weight gain
Muscle weakness
Extremity pain
Breast pain
Anorexia
Insomnia
Fatigue
Mood liability
Somnolence
Acute psychosis
Edema
Hypotension
Syncope
Neutropenia
Increased bilirubin
Increased CPK
Decreased haematocrit
Decreased haemoglobin
Increased potassium
Increased transaminases
Increased triglycerides

Precautions

Precautions

Extra caution should be taken by women of childbearing age, as it may restore fertility. It should not be given during pregnancy or during breastfeeding. This should not be given to people who will be operating machinery or those who will operate machines.

Take precautions in people with the following conditions:

History of psychotic disorders
Patients treated with dopamine agonists for Parkinson’s disease such as Quinagolide especially at high doses
Elderly
Kidney problems
Liver problems

Interactions

Quinagolide may interact with the following medicines:

Metoclopramide
Antipsychotic drugs that have dopamine antagonistic action

Overdose & Brands

Symptoms of Quinagolide may include the following:

Dizziness
Drowsiness
Headache
Severe nausea
Vomiting
Hallucinations
Hypotension
Collapse

Available Brand/s:

Norprolac