QUELICIN

Do not use Quelicin in people with the following conditions:

• Hypersensitivity
• Personal or family history of malignant hyperthermia (MH): Succinylcholine chloride can trigger malignant hyperthermia, a rare but potentially fatal condition characterized by a rapid rise in body temperature, muscle rigidity, and metabolic disturbances. Individuals with a personal or family history of MH should avoid succinylcholine chloride.
• History of hyperkalemia: Succinylcholine chloride can cause an increase in potassium levels in the blood. Individuals with a history of hyperkalemia (high blood potassium levels) should avoid succinylcholine chloride, as it can further elevate potassium levels and potentially lead to serious cardiac complications.
• Certain muscular disorders: Succinylcholine chloride should be used with caution or avoided in individuals with certain muscular disorders, such as myasthenia gravis, muscular dystrophy, or other conditions affecting neuromuscular function. These conditions can increase the risk of adverse reactions or complications with succinylcholine chloride.
• Serious burns or trauma: In individuals with extensive burns or traumatic injuries, succinylcholine chloride may increase the risk of developing hyperkalemia or rhabdomyolysis (breakdown of muscle tissue). These conditions can be exacerbated by succinylcholine chloride and lead to serious complications.

Quelicin may have the following side effects:

• Muscle pain: Succinylcholine chloride can cause muscle pain or soreness after administration. This discomfort is usually temporary and resolves on its own.
• Fasciculations: Succinylcholine chloride may cause fasciculations, which are involuntary muscle twitches or contractions. These typically occur before or after muscle relaxation and are generally transient
• Increased intraocular pressure: Succinylcholine chloride can temporarily increase intraocular pressure, which may be a concern for individuals with certain eye conditions or glaucoma. Precautions should be taken in such cases.
• Bradycardia or tachycardia: Succinylcholine chloride can cause changes in heart rate, leading to either a slow heart rate (bradycardia) or a rapid heart rate (tachycardia). These effects are usually temporary and resolve without intervention
• Hypotension: Succinylcholine chloride may cause a drop in blood pressure, leading to hypotension. This effect is typically short-lived and can be managed by appropriate medical interventions if necessary.
• Allergic reactions: Although rare, succinylcholine chloride can cause allergic reactions in some individuals. Symptoms may include rash, itching, swelling, difficulty breathing, or anaphylaxis. Immediate medical attention is necessary if these symptoms occur
• Hyperkalemia: Succinylcholine chloride can trigger an increase in potassium levels in the blood, particularly in individuals with certain conditions or predispositions. This can potentially lead to cardiac complications, especially in individuals with underlying heart disease or kidney dysfunction.

Keep in mind that your physician has recommended this drug since he or she has known that the advantage to you is more noteworthy than the risk of adverse reactions. Many individuals utilizing this medicine don’t have serious side effects.

A serious allergy to this medication is uncommon. In any case, seek emergency medical help if you see any manifestations of a serious allergic response, including a rash, tingling or swelling particularly of the face or tongue or throat, dizziness or difficulty in breathing.

This is not a complete list of side effects. If you see other effects not recorded above, contact your physician or pharmacist.

Precautions

Take extra caution in patients with the following medical conditions:

• Use caution in patients with certain medical conditions: Succinylcholine chloride should be used with caution in individuals with certain medical conditions, such as cardiovascular disease, electrolyte imbalances, kidney or liver dysfunction, neuromuscular disorders, or a history of malignant hyperthermia. These conditions may increase the risk of adverse effects or complications
• Avoid prolonged use: Succinylcholine chloride is typically used as a short-acting muscle relaxant for procedures or surgeries. Prolonged or repeated use should be avoided, as it may increase the risk of certain side effects, such as hyperkalemia or myopathy
• Monitor for hypersensitivity or allergic reactions: Allergic reactions to succinylcholine chloride can occur, although they are rare. It’s important to monitor patients for any signs of hypersensitivity or allergic reactions, such as rash, itching, swelling, difficulty breathing, or anaphylaxis. Immediate medical attention should be sought if these symptoms occur.
• Be cautious in pediatric patients: Succinylcholine chloride can be used in pediatric patients, but special caution should be exercised, as they may be more susceptible to certain adverse effects or complications. Dosing should be based on weight and age, and monitoring should be intensified.
• Avoid use in patients with a family history of malignant hyperthermia: Succinylcholine chloride can trigger malignant hyperthermia (MH) in individuals predisposed to this condition. If a patient has a known family history of MH, alternative medications should be considered to avoid the risk of severe complications.

Prior to taking this medicine, tell your physician or pharmacist if you are allergic to it, or if you have some other hypersensitivities. This drug may contain inert ingredients which can cause unfavorable side effects or different issues. Talk with your pharmacist for more information.

Interactions

Quelicin may interact with the following medicines:

• Medications affecting neuromuscular function: Medications that affect neuromuscular function, such as certain antibiotics (e.g., aminoglycosides, tetracyclines), local anesthetics (e.g., lidocaine), or calcium channel blockers, may interact with succinylcholine chloride.
• These interactions can potentiate or prolong the effects of succinylcholine chloride, leading to increased muscle relaxation or respiratory depression. Close monitoring and dose adjustments may be necessary
• Medications prolonging QT interval: Succinylcholine chloride can potentially prolong the QT interval on an electrocardiogram (ECG). Therefore, caution should be exercised when using succinylcholine chloride in combination with medications that also have QT-prolonging effects, such as certain antiarrhythmics (e.g., amiodarone, sotalol), antipsychotics (e.g., haloperidol), or antidepressants (e.g., tricyclic antidepressants). Close monitoring of cardiac function is recommended.
• Medications affecting potassium levels: Succinylcholine chloride can cause an increase in potassium levels in the blood, particularly in individuals with certain predispositions or conditions. Medications that can further increase potassium levels, such as potassium-sparing diuretics (e.g., spironolactone), ACE inhibitors, or angiotensin receptor blockers (ARBs), may increase the risk of hyperkalemia. Monitoring potassium levels and considering alternative muscle relaxants may be necessary.
• Medical conditions affecting neuromuscular function: Certain medical conditions, such as neuromuscular disorders (e.g., myasthenia gravis), electrolyte imbalances, or liver dysfunction, can interact with succinylcholine chloride. These conditions may alter the response to succinylcholine chloride or increase the risk of adverse effects. Close monitoring and dose adjustments may be required.
• Malignant hyperthermia (MH): Succinylcholine chloride can trigger malignant hyperthermia in individuals with a genetic predisposition to this condition. Therefore, it should be avoided in patients with a known family history of MH. Alternative medications should be considered for these individuals.

Inform your physician about the drugs you take including over-the-counter medications, prescribed drugs, supplements and vitamins.

This is not a complete list of drug interactions. Approach your physician or pharmacist for more details.

The effects of certain medications can change if you consume different medications or herbal products simultaneously. This can build your risk for side effects or may cause your drugs not to work effectively. These interactions are conceivable, yet don’t generally happen. Your physician or pharmacist can prevent or oversee interactions by changing how you utilize your prescriptions or by close checking.

While utilizing this drug, don’t start, stop, or change the dose of other medicines you are using without your physician’s advice.

If you suspect an overdose, contact your doctor right away.

Available Brands:

• Quelicin