PSEUDOEPHEDRINE-IBUPROFEN

Pseudoephedrine is a decongestant that relieves nasal congestion by shrinking the blood vessels in the nasal passages. Ibuprofen works in the brain to help decrease pain.

Uses

This combination medication is used to temporarily relieve symptoms caused by the common colds, upper respiratory infections and allergies. This medication may also be used in other conditions to be determined by your doctor.

Warnings

Do not use this drug:

If you are allergic to any ingredient in Pseudoephedrine and Ibuprofen
If you have recently had or will be having bypass heart surgery
If you have the following medical condition: severe high blood pressure, severe heart blood vessel disease, rapid heartbeat, or severe heart problems
If you have had a severe allergic reaction to aspirin or an NSAID (eg, Celecoxib, Ibuprofen)
If you have taken Furazolidone or a Monoamine Oxidase Inhibitor (MAOI) (eg, Phenelzine) within the last 14 days
If you are in the last 3 months of pregnancy

Side Effects

Common side effects may include:

Constipation
Diarrhea
Dizziness
Drowsiness
Excitability
Headache
Loss of Appetite
Nausea
Nervousness or Anxiety
Trouble Sleeping
Upset Stomach
Vomiting
Weakness

Severe side effects may include:

Severe Allergic Reactions (Rash; Hives; Itching; Difficulty Breathing; Tightness in the Chest; Swelling of the Mouth, Face, Lips, or Tongue)
Bloody or Black, Tarry Stools
Change in the Amount of Urine Produced
Chest Pain
Confusion
Dark Urine
Depression
Fainting
Fast or Irregular Heartbeat
Fever, Chills, or Persistent Sore Throat
Hallucinations
Mood or Mental Changes
Numbness of an Arm or Leg
One-Sided Weakness
Red, Swollen, Blistered, or Peeling Skin
Ringing in the Ears
Seizures
Severe Dizziness
Lightheadedness or Headache
Severe Drowsiness
Severe or Persistent Stomach Pain or Nausea
Severe Vomiting
Shortness of Breath
Stiff Neck
Sudden or Unexplained Weight Gain
Swelling of Hands, Legs, or Feet
Tremor
Unusual Bruising or Bleeding
Unusual Joint or Muscle Pain
Unusual Tiredness or Weakness
Vision or Speech Changes
Vomit that Looks Like Coffee Grounds
Yellowing of Skin or Eyes

Seek immediate medical attention if you experience any of these serious side effects.

Precautions

Precautions

Before using this medication, tell your doctor or pharmacist:

If you are allergic to any content of this drug or if you have other allergies.
If you are pregnant, planning to become pregnant, or are breast-feeding
If you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
If you have a medical history of:
- Adrenal Gland Problems (eg, Adrenal Gland Tumor)
- Asthma, Stomach or Bowel Problems (eg, Bleeding, Perforation, Ulcers, Persistent or Returning Stomach Pain or Heartburn)
- Heart Problems (eg, Heart Failure)
- High Blood Pressure
- Diabetes
- Blood Disorders
- Bleeding or Clotting Problems
- Blood Vessel Problems
- Stroke
- Glaucoma or Increased Eye Pressure
- An Enlarged Prostate or other Prostate Problems
- Seizures
- An Overactive Thyroid
- Kidney Problems
- Liver Problems (eg, Hepatitis)
If you have a history of swelling or fluid buildup, lupus, asthma, growths in the nose (nasal polyps), or mouth inflammation
If you are dehydrated or have low fluid volume (eg, caused by diarrhea, not drinking fluids, vomiting)
If you have poor health or low blood sodium levels and if you drink alcohol or a history of alcohol abuse.

Interactions

Drug interactions may either lessen the effectiveness of this drug or heighten the risk for severe side effects. It’s important to inform your doctor all the medication including prescription and non-prescription and herbal medicines you are taking or going to take.

Possible interactions with this drug are:

Anticoagulants (eg, Warfarin)
Aspirin
Corticosteroids (eg, Prednisone)
Heparin
Selective Serotonin Reuptake Inhibitors (SSRIs) (eg, Fluoxetine)
Beta-Blockers (Eg, Propranolol)
Catechol-O-Methyltransferase (COMT) Inhibitors (eg, Tolcapone)
Furazolidone
Indomethacin
Isoniazid
Maois (eg, Phenelzine)
Probenecid
Tricyclic Antidepressants (eg, Amitriptyline)
Bromocriptine
Cyclosporine
Hydantoins (eg, Phenytoin)
Lithium
Methotrexate
Quinolones (eg, Ciprofloxacin)
Angiotensin-Converting Enzyme (ACE) Inhibitors (eg, Enalapril)
Diuretics (eg, Furosemide, Hydrochlorothiazide)
Guanadrel
Guanethidine
Mecamylamine
Methyldopa
Reserpine

Overdose & Brands

Call emergency hotline if someone has overdosed and has serious symptoms such as passing out or trouble breathing.

Symptoms of overdose may include:

Blurred Vision
Confusion
Hallucinations
Seizures
Severe Dizziness
Lightheadedness or Headache
Severe Drowsiness
Severe Nausea or Stomach Pain
Slow or Troubled Breathing
Unusual Bleeding or Bruising
Unusually Fast, Slow, or Irregular Heartbeat
Vomit that Looks Like Coffee Grounds