Periciazine is a phenothiazine with a piperidine side chain that has a stronger sedative effect and modest antipsychotic effects. It reduces the quantity of hypothalamic and hypophyseal hormones by blocking subcortical dopamine receptors in the brain.

Use this medication precisely as recommended by your physician. Follow the prescription of your doctor carefully.

The medication dose your physician has given is based on your condition, other medications or food supplements you may take, and your reaction to treatment. To diminish your risks for adverse effects, don’t increase your dosage, take it regularly, or take it as instructed by your physician. Adverse events may still happen even at usual prescription dosages.

If your physician requests you to use this drug consistently, use it regularly to get the most benefits from it. To make you remember it better, take it at a fixed time every day.

Your doctor may need to modify your dosages to ease your symptoms or if you develop adverse reactions.

If you have any inquiries with regards to information, ask your physician or pharmacist.

Periciazine is used in the following conditions:

  • Psychoses
  • Schizophrenia
  • Aggression
  • Anxiety
  • Impulsive behavior
  • Psychomotor agitation

This medicine may be recommended for different uses. Approach your physician or pharmacist for more information.

Do not use Periciazine in people with the following conditions:

  • Altered states of consciousness or coma
  • Parkinson’s disease
  • Seizures that go untreated
  • Collapse of the circulatory system
  • Narrow-angle glaucoma 
  • Pheochromocytoma
  • Myasthenia gravis
  • Hypothyroidism
  • Hypertrophy of the prostate
  • Insufficiency of the liver and kidneys.
  • Concomitant use with spinal or regional anesthesia

Periciazine may have the following side effects:

  • Impotence
  • Priapism
  • Respiratory depression
  • Nasal congestion
  • Asthma
  • Laryngeal edema
  • Pneumonia
  • Rashes
  • Diaphoresis
  • Deep vein thrombosis
  • Akathisia
  • Tardive dyskinesia
  • Hyperprolactinaemia
  • Pigmentary retinopathy
  • Corneal deposits
  • Changes in skin pigmentation 
  • Impaired body temperature regulation
  • Weight gain
  • Glucose intolerance
  • Hyperglycemia
  • Diabetic ketoacidosis
  • Increased prolactin level
  • Leucopenia
  • Atrioventricular block
  • Dry mouth
  • Neuroleptic malignant syndrome
  • Anticholinergic effects
  • Altered cardiac conduction
  • QT prolongation
  • Orthostatic hypotension
  • Venous thromboembolism
  • Blood dyscrasias 
  • CNS depression
  • Esophageal dysmotility and aspiration
  • Extrapyramidal symptoms
  • Pseudoparkinsonism
  • Acute dystonic reactions
  • Nausea
  • Constipation
  • Diarrhea
  • Cholestasis
  • Fecal impaction
  • Increased appetite
  • Jaundice
  • Liver injury
  • Angioedema
  • Insomnia
  • Agitation
  • Drowsiness
  • Headache
  • Dizziness
  • Paradoxical psychosis
  • Urinary incontinence
  • Galactorrhea
  • Gynecomastia
  • Amenorrhea

Potentially Fatal: 

  • Pulmonary embolism
  • Ventricular arrhythmia

Keep in mind that your physician has recommended this drug since he or she has known that the advantage to you is more noteworthy than the risk of adverse reactions. Many individuals utilizing this medicine don’t have serious side effects. 

A serious allergy to this medication is uncommon. In any case, seek emergency medical help if you see any manifestations of a serious allergic response, including a rash, tingling or swelling particularly of the face or tongue or throat, dizziness or difficulty in breathing.

This is not a complete list of side effects. If you see other effects not recorded above, contact your physician or pharmacist.

Take extra caution in patients with the following medical conditions:

  • Patient suffering from epilepsy
  • Seizures in the past
  • Cerebrovascular disease (CVD)
  • CVD
  • Urinary retention
  • Long QT syndrome
  • Deficiency in electrolytes
  • Reduced gastrointestinal motility
  • Ileus paralytic
  • Xerostomia
  • Other issues with vision
  • Aspiration pneumonia risk factors
  • Dementia with Lewy Bodies
  • Diabetes mellitus
  • Trauma to the head
  • Damage to the brain
  • Alcoholism
  • Hypovolaemia
  • Thrombosis risk factors
  • Prolactin-dependent cancers, such as breast cancer
  • Children
  • Elderly
  • Pregnancy
  • Lactation

Prior to taking this medicine, tell your physician or pharmacist if you are allergic to it, or if you have some other hypersensitivities. This drug may contain inert ingredients which can cause unfavorable side effects or different issues. Talk with your pharmacist for more information.


Periciazine may interact with the following medicines:

  • Guanethidine
  • Adrenaline
  • Carbamazepine
  • Amitriptyline
  • Antacids
  • Anti-Parkinson drugs
  • Propranolol
  • Phenobarbital
  • Antiarrhythmics
  • Antidepressants
  • Antipsychotics
  • Antihypertensive agents
  • Barbiturates
  • Benzodiazepines
  • Sedatives
  • Levodopa
  • Clonidine

Inform your physician about the drugs you take including over-the-counter medications, prescribed drugs, supplements and vitamins.

This is not a complete list of drug interactions. Approach your physician or pharmacist for more details.

The effects of certain medications can change if you consume different medications or herbal products simultaneously. This can build your risk for side effects or maycause your drugs not to work effectively. These interactions are conceivable, yet don’t generally happen. Your physician or pharmacist can prevent or oversee interactions by changing how you utilize your prescriptions or by close checking.

While utilizing this drug, don’t start, stop, or change the dose of other medicines you are using without your physician’s advice.

Symptoms of overdose may include the following: 

  • Drowsiness
  • Consciousness loss
  • Hypotension
  • Tachycardia
  • Ventricular arrhythmia
  • ECG changes
  • Hypothermia
  • Severe extrapyramidal dyskinesias

Seek medical help immediately.

Available Brands:

  • Neuleptil

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