COMMON BRAND NAME(S): Serax
GENERIC NAME(S): OXAZEPAM
Description: Oxazepam is a short-acting benzodiazepine which enhancing the GABA inhibitory effects a calming and anti-seizure effect.
Pharmacokinetics:
Absorption: Well absorbed from the GI tract. Time to peak plasma concentration: Approx 2-3 hr.
Distribution: It crosses the placenta and detected in breast milk. Plasma protein binding: Approx 97%.
Metabolism: Undergoes hepatic conjugation to produce the major inactive glucuronide metabolite.
Excretion: Via urine as inactive glucuronide conjugate. Elimination half-life: Approx 4-15 hr.