COMMON BRAND NAME(S): Alli, Xenical
GENERIC NAME(S): ORLISTAT
Description: Orlistat is a reversible gastric and pancreatic lipase inhibitor. It exerts antiobesity effects by limiting the absorption of dietary fats through inhibition of triglyceride hydrolysis. It does not exert appetite suppressant effects.
Onset: 24-48 hr.
Duration: 48-72 hr.
Absorption: Minimally absorbed (oral).
Metabolism: Metabolised to inactive metabolites within the GI wall.
Excretion: Mainly via faeces (83% as unchanged drug).hr.