Octopamine or β,4-dihydroxyphenethylamine is a compound that was originally extracted from the salivary glands of octopus. Just like nonadrenaline, Octopamine is released during stress. It is also responsible for the physiological changes in the fight-or-flight occurrences. The potential of this supplement has been seen to help athletes and body-builders in toning down their muscles as well as to give them an ergogenic performance.