For simple cases, a laboratory diagnosis is often not necessary. It is possible to diagnose complex instances by separating the virus:
- via culturing of feces or upper respiratory tract samples
- from cerebrospinal fluid samples, biopsy samples, or skin lesions
Both viral culture and molecular methods may be used, including:
- Polymerase chain reaction
For precise virus strain characterization, cultivation to produce a viral isolation is preferable. Blood samples taken during the acute and convalescent periods of sickness might show a 4-fold increase in neutralizing antibody levels, which indicates a recent infection.
There is no particular therapy for non-polio enterovirus infections other than polio. Usually, people with non-polio enterovirus infections that produce moderate illness just need to address their symptoms. This includes taking over-the-counter cold medicines as necessary and drinking enough water to remain hydrated. Most folks fully recover. However, certain conditions brought on by enteroviruses other than polio might be serious enough to need hospitalization. You should speak with your doctor if your symptoms cause you any worry.