NITROFURANTOIN

Nitrofurantoin disrupts glucose metabolism by blocking bacterial acetyl coenzyme-A. It also prevents the creation of bacterial cell wall, and the production of RNA, DNA, aerobic energy metabolism, and protein.

Use this medication precisely as recommended by your physician. Follow the prescription of your doctor carefully.

The medication dose your physician has given is based on your condition, other medications or food supplements you may take, and your reaction to treatment. To diminish your risks for adverse effects, don’t increase your dosage, take it regularly, or take it as instructed by your physician. Adverse events may still happen even at usual prescription dosages.

If your physician requests you to use this drug consistently, use it regularly to get the most benefits from it. To make you remember it better, take it at a fixed time every day.

Your doctor may need to modify your dosages to ease your symptoms or if you develop adverse reactions.

If you have any inquiries with regards to information, ask your physician or pharmacist.

Uses

Nitrofurantoin is used in the following conditions:

Prophylaxis of surgical infections
Acute uncomplicated urinary tract infections

This medicine may be recommended for different uses. Approach your physician or pharmacist for more information.

Warnings

Do not use Nitrofurantoin in people with the following conditions:

Simultaneous vaccination with live polio vaccines
Recent nitrofurantoin usage linked to hepatic impairment
Cholestatic jaundice history
CrCl <60 ml/min or eGFR <45 mL/min
High level of serum creatinine
Extreme renal impairment
Term pregnancy (during labour and delivery).
Infants <1 month
G6PD deficiency
Acute porphyria
Hypersensitivity

Side Effects

Nitrofurantoin may have the following side effects:

Alopecia
Pruritus
Acute pulmonary hypersensitivity responses
Drowsiness
Dizziness
Arthralgia
Anorexia
Urticaria
Angioedema
Anaphylactoid reactions
Asthenia
Malaise
Chills
Fever
Emesis
Constipation
Abdominal pain
Dyspepsia
Diarrhea
Amblyopia
Angina
Aplastic anemia
Agranulocytosis
Hemolytic anemia
C. difficile-associated diarrhea
Superinfection
Peripheral neuropathy
Optic neuritis

Potentially Fatal:

Peripheral neuropathy
Chronic, subacute, or acute pulmonary toxicity
Hepatic necrosis
Hepatitis
Cholestatic jaundice

Keep in mind that your physician has recommended this drug since he or she has known that the advantage to you is more noteworthy than the risk of adverse reactions. Many individuals utilizing this medicine don’t have serious side effects.

A serious allergy to this medication is uncommon. In any case, seek emergency medical help if you see any manifestations of a serious allergic response, including a rash, tingling or swelling particularly of the face or tongue or throat, dizziness or difficulty in breathing.

This is not a complete list of side effects. If you see other effects not recorded above, contact your physician or pharmacist.

Precautions

Take extra caution in patients with the following medical conditions:

Elderly
Children
Lactation
Allergic diathesis
Neurological disorders
Pre-existing pulmonary diseases
Debilitating diseases
Electrolyte imbalance
Vitamin B deficiency
Diabetes mellitus
Patient with anemia

Prior to taking this medicine, tell your physician or pharmacist if you are allergic to it, or if you have some other hypersensitivities. This drug may contain inert ingredients which can cause unfavorable side effects or different issues. Talk with your pharmacist for more information.

Interactions

Nitrofurantoin may interact with the following medicines:

Live polio vaccine
Norfloxacin
Acetazolamide
Quinolone antibacterials
Sulfinpyrazone
Probenecid
Mg trisilicate

Inform your physician about the drugs you take including over-the-counter medications, prescribed drugs, supplements and vitamins.

This is not a complete list of drug interactions. Approach your physician or pharmacist for more details.

The effects of certain medications can change if you consume different medications or herbal products simultaneously. This can build your risk for side effects or may cause your drugs not to work effectively. These interactions are conceivable, yet don’t generally happen. Your physician or pharmacist can prevent or oversee interactions by changing how you utilize your prescriptions or by close checking.

While utilizing this drug, don’t start, stop, or change the dose of other medicines you are using without your physician’s advice.

Overdose & Brands

Symptoms of overdose may include the following:

Vomiting
Nausea
Gastric irritation

Seek medical help immediately.

Available Brands:

Urontin
Nitro
Macrodantin