NEBIVOLOL

COMMON BRAND NAME(S): Bystolic

GENERIC NAME(S): NEBIVOLOL HCL

 

Description: Nebivolol is a beta blocker used to lower heart rate, blood pressure and strain on the heart

Pharmacokinetics:

Absorption: Rapidly absorbed from the GI tract. Time to peak plasma concentration: 1.5-4 hr.

Distribution: Volume of distribution: 8-12 L/kg. Plasma protein binding: Approx 98% (mainly to albumin).

Metabolism: Undergoes extensive hepatic metabolism via glucuronidation and via alicyclic and aromatic hydroxylation, N-dealkylation by CYP2D6 isoenzyme.

Excretion: Via urine and faeces (as metabolites). Elimination half-life: Approx 10 hr (nebivolol); approx 24 hr (hydroxy metabolites).

  • Used for
    • High Blood pressure treatment
      • Lowers high blood pressure whichs helps prevent strokes, heart attacks, and kidney problems
    • Belongs to a class of drugs known as beta blockers which blocks the action of certain natural substances like epinephrine, on the heart and blood vessels
      • Lowers heart rate, blood pressure, and strain on the heart

 

  • May also be used to prevent chest pain (angina), heart failure, and to improve survival after a heart attack.

 

How to use nebivolol

  • Always refer to your doctors instructions before taking this medication. Duration and dosage will be determined by your medical condition and its response to the medication. Make sure to take this mediciation in the prescribed amount and time period even after symptoms disappear. Discontinuing the medication before completion of treatment may cause incomplete treatment of condition. If Symptoms persist, consult your doctor

 

Taken by mouth; With or without food; usually once a day;

    • Do not discontinue taking this medication without doctor’s consult to prevent effects such as

    chest pain, heart attack, and irregular heartbeat

      • Minor side effects (if these symptoms persist or worsen, inform your doctor)
        • Headache, dizziness, tiredness, nausea, slow heartbeat, and trouble sleeping

       

      • may reduce blood flow to your hands and feet, causing them to feel cold. Smoking may worsen this effect. Dress warmly and avoid tobacco use
      • Serious side effects (inform your doctor immediately)
        • symptoms of asthma (for example, feelings of tightness in the chest, shortness of breath, cough, wheezing), blue fingers/toes, fainting, very slow heartbeat, new or worsening symptoms of heart failure (such as swelling ankles/feet, severe tiredness, shortness of breath, unexplained/sudden weight gain), mental/mood changes (such as confusion, mood swings, depression).

       

      • Severe allergic reactions are rare. Get immediate medical help if you notice the following:
        • Rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing
      • Precautions:
        • Inform your doctor
          • Allergy to the medication or any allergies
          • Medical History of blood circulation problems (such as Raynaud’s disease, peripheral vascular disease), breathing problems (such as asthma, chronic bronchitis, emphysema), heart problems (such as heart failure, previous heart attack, heart rhythm problems), kidney problems, liver problems, mental/mood disorders (such as depression), a certain muscle disease (myasthenia gravis), overactive thyroid disease (hyperthyroidism), serious allergic reactions, including those needing treatment with epinephrine

         

        • May cause dizziness

         

        • Should only be used when there is a clear need during pregnancy as it may harm an unborn baby. Babies born to mothers taking this drug during pregnancy may have a low birth weight and require monitoring for problems such as low blood pressure and slow heartbeat If you are planning to be pregnant or think you may be pregnant, discuss the risks and benefits of use with your doctor.

         

        • It is not known if this drug passes into breast milk. Before breast-feeding, consult your physician.

         

         

        Interactions:

        Taking multiple drugs may affect how medications work and/or cause unwanted side effects. List down all the medications you are taking and inform your physician and pharmacist. Do not take, discontinue, or alter any dose of medications without prior approval of your physician.

         

        • Products that may interact with this medication include:
          • fingolimod

         

        double check the labels on all medications you are currently taking especially cough-and-cold products since they may contain components that could increase your blood pressure or heart rate

      • Overdose: If overdose is suspected, contact a poison control center or emergency room immediately.NotesLifestyle changes such as stress reduction programs, exercise, and dietary changes may increase the effectiveness of this medicine. Talk to your doctor or pharmacist about lifestyle changes that might benefit you.

         

         

        Missed Dose

        If you miss a dose, take it as soon as you remember. If it is near the time of the next dose, skip the missed dose and As soon as you remember, take a regular dose or if the time of the next dose is near, wait for it before taking another dose and resume your usual schedule. Do not increase the dose to compensate for the missed dose.

         

        Storage

        • Room temperature
        • Do not expose to light and moisture
        • Do not store in the bathroom
        • Keep all medications away from pets and children

         

        Brands:

         

        Available Brands:

        Nebicar [ OEP Phils ]

        Nebil [ Getz Pharma ]

        Nebilet [ A. Menarini ]

        Toricard-5 [ Torrent ]

Related Articles

ULTRAVIST

UsesWarningsSide EffectsPrecautionsOverdose & BrandsUses Ultravist is used in the following conditions: Radiographic Imaging: Iopromide injection is utilized to enhance the [...]

ULTRAMOX

UsesWarningsSide EffectsPrecautionsOverdose & BrandsUses Ultramox is used in the following conditions: Respiratory Infections: Amoxicillin is often used to treat respiratory [...]

ULTRALIV

UsesWarningsSide EffectsPrecautionsOverdose & BrandsUses Ultraliv is used in the following conditions: Carnitine Orotate: Carnitine orotate is a combination of L-carnitine [...]