COMMON BRAND NAME(S): Starlix
GENERIC NAME(S): NATEGLINIDE
Description: Nateglinide is a nonsulfonylurea hypoglycaemic agent that aids in reducing post-meal increase of glucose levels.
Onset: Approx 20 min.
Duration: 4 hr.
Pharmacokinetics:
Absorption: Rapidly absorbed; peak plasma concentrations within 1 hr (oral).
Distribution: Protein-binding: 98%, primarily to albumin.
Metabolism: Hepatic via hydroxylation followed by glucuronidation; converted to metabolites.
Excretion: Via urine (16% unchanged drug); faeces (10%). Elimination half-life: 1.5 hr.