Multiple peripheral neuritis is an illness that results from a nerve injury outside of the spinal cord and the brain. It may result in discomfort, numbness, and weakness, most often in the feet and the hands. It may also affect other regions and activities of the body, like circulation, urination, and digestion.

People suffering from multiple peripheral neuritis report their discomfort as tingling, burning, or stabbing. This condition may be relieved with medication.


Among the signs and symptoms of Multiple peripheral neuritis are:

  • Throbbing, jabbing, sharp, or scorching discomfort
  • Extreme touch sensitivity
  • Pain during normal activities, such as foot pain while weighted or beneath a blanket.
  • Muscle weakness
  • Paralysis happens when the motor nerves are damaged.
  • Tingling, prickling, or numbness in the hands and feet may progress to the arms and legs.
  • Falling and a lack of coordination
  • A feeling that you have gloves or socks on when you don’t.

Autonomic nerve dysfunction symptoms and signs may include:

  • Digestion, bowel, or bladder problems
  • Cannot be able to sweat or excessive sweating
  • Low blood pressure causes dizziness or lightheadedness
  • Heat intolerance


There are several possible causes of multiple peripheral neuritis. Aside from a physical examination (including blood tests), diagnosis usually necessitates the following:

  • Neurological examination. The physician could examine the tendon reflexes, as well as your muscle strength and tone, the ability to sense particular sensations, posture, and coordinate your movements.
  • A comprehensive medical history. The healthcare provider will review your medical history, including toxicity exposure, lifestyle, symptoms, drinking habits, and a family history of neurological problems.


Your professional health provider may suggest the following tests:

  • Nerve function tests like Electromyography (EMG)
  • Nerve biopsy
  • Skin biopsy
  • Blood tests
  • Imaging tests like CT or MRI scans


In addition to those used to treat conditions related to multiple peripheral neuritis, medications used to alleviate multiple peripheral neuritis signs and symptoms include:

  • Anti-seizure medications. Gabapentin and pregabalin
  • Pain relievers. Nonsteroidal anti-inflammatory drugs and tramadol
  • Topical treatments. Capsaicin cream and lidocaine patches
  • Antidepressants. Tricyclic antidepressants (amitriptyline), doxepin, serotonin, venlafaxine (Effexor XR) and desvenlafaxine (Pristiq) 


Several procedures and therapies may be used to alleviate the signs and symptoms of multiple peripheral neuritis. These are some examples:

  • Physical therapy
  • Transcutaneous electrical nerve stimulation (TENS)
  • Plasma exchange and intravenous immune globulin
  • Surgery

Related Articles


Overview and FactsTypes and SymptomsDiagnosis & MedicationsOverview and Facts Referred pain is a phenomenon where pain is perceived at a [...]


Overview and FactsTypes and SymptomsDiagnosis & MedicationsOverview and Facts Quinoline yellow is a synthetic food colorant commonly used in the [...]


Overview and FactsTypes and SymptomsDiagnosis & MedicationsOverview and Facts Pneumothorax is a condition characterized by the presence of air in [...]