MIANSERIN

Mianserin stimulates central noradrenergic neurotransmission by reducing noradrenaline reuptake and blocking the presynaptic 2-autoreceptor. It also interacts with serotonergic receptors in the CNS, antihistamine properties, and 1 antagonistic activity.

Use this medication precisely as recommended by your physician. Follow the prescription of your doctor carefully.

The medication dose your physician has given is based on your condition, other medications or food supplements you may take, and your reaction to treatment. To diminish your risks for adverse effects, don’t increase your dosage, take it regularly, or take it as instructed by your physician. Adverse events may still happen even at usual prescription dosages.

If your physician requests you to use this drug consistently, use it regularly to get the most benefits from it. To make you remember it better, take it at a fixed time every day.

Your doctor may need to modify your dosages to ease your symptoms or if you develop adverse reactions.

If you have any inquiries with regards to information, ask your physician or pharmacist.

Uses

Mianserin is used in the following conditions:

Depression

This medicine may be recommended for different uses. Approach your physician or pharmacist for more information.

Warnings

Do not use Mianserin in people with the following conditions:

Mania
Concomitant use with MAOIs
Lactation
Severe hepatic impairment

Side Effects

Mianserin may have the following side effects:

Blurred vision
Urinary retention
Granulocytopenia
Suicidal ideation and behaviour
Constipation
Xerostomia
Hyponatraemia
Arthralgia
Precipitate shift to mania or hypomania
Bone fracture
Hepatic disorder
Jaundice
Non-puerperal lactation
Orthostatic hypotension
QT prolongation
Ventricular arrhythmias
Agranulocytosis
Leucopenia
Aplastic anemia
Sweating
Arthritis
Edema
Nipple tenderness
Rash
Polyarthropathy
Dizziness
Headache
Tremor
Seizure
Withdrawal symptoms
Gynaecomastia

Potentially Fatal:

Serotonin syndrome

Keep in mind that your physician has recommended this drug since he or she has known that the advantage to you is more noteworthy than the risk of adverse reactions. Many individuals utilizing this medicine don’t have serious side effects.

A serious allergy to this medication is uncommon. In any case, seek emergency medical help if you see any manifestations of a serious allergic response, including a rash, tingling or swelling particularly of the face or tongue or throat, dizziness or difficulty in breathing.

This is not a complete list of side effects. If you see other effects not recorded above, contact your physician or pharmacist.

Precautions

Take extra caution in patients with the following medical conditions:

Paralytic ileus
Benign prostatic hyperplasia
Xerostomia
Increased intraocular pressure
Urinary retention
Visual problems
Suicidal ideation or history of suicide-related event
Existing or history of CV disease
Congenital long QT syndrome
Patient undergoing surgery
Renal and hepatic impairment
Elderly
Structural heart disease, or left ventricular dysfunction
Brain damage
Diabetes mellitus
Bipolar disorder
Pheochromocytoma
Cerebrovascular disease
Hypovolaemia
History of seizure
Head trauma
Decreased gastrointestinal motility
Angle-closure glaucoma
Female
Pregnancy

Prior to taking this medicine, tell your physician or pharmacist if you are allergic to it, or if you have some other hypersensitivities. This drug may contain inert ingredients which can cause unfavorable side effects or different issues. Talk with your pharmacist for more information.

Interactions

Mianserin may interact with the following medicines:

Phenytoin
Atomoxetine
Diazoxide
Hydralazine
Antiepileptics
Barbiturates
Anxiolytics
Nitroprusside
Antihistamine
Antimuscarinics
Carbamazepine
Phenobarbital
Primidone
Hypnotics
Antipsychotics

Potentially Fatal:

Lithium
Tramadol
MAOIs
Linezolid
IV methylene blue
Fentanyl
TCAs
Triptans
Buspirone
Tryptophan

Inform your physician about the drugs you take including over-the-counter medications, prescribed drugs, supplements and vitamins.

This is not a complete list of drug interactions. Approach your physician or pharmacist for more details.

The effects of certain medications can change if you consume different medications or herbal products simultaneously. This can build your risk for side effects or may cause your drugs not to work effectively. These interactions are conceivable, yet don’t generally happen. Your physician or pharmacist can prevent or oversee interactions by changing how you utilize your prescriptions or by close checking.

While utilizing this drug, don’t start, stop, or change the dose of other medicines you are using without your physician’s advice.

Overdose & Brands

Symptoms of overdose may include the following:

Nausea
Hypertension
Respiratory depression
ECG abnormalities
Nystagmus
Constricted or dilated pupils
Prolonged sedation
Convulsions
Coma
Ataxia
Vomiting
Dry mouth
Bradycardia
Tachycardia
Hypotension
1st degree to complete heart block

Seek medical help immediately.

Available Brands:

Tolvon