MEPROBAMATE

COMMON BRAND NAME(S): Equanil

GENERIC NAME(S): MEPROBAMATE

 

Description: Meprobamate is a carbamate derivative with CNS depressant actions similar to those of barbiturates. It can be used as an anxiolytic, sedative or muscle relaxant.

Pharmacokinetics:

Absorption: Well absorbed form GI tract (oral) peak plasma concentrations within 1-3 hr.

Distribution: Widely distributed. 20% plasma protein bound. Crosses placenta and into breast milk.

Metabolism: Hepatic metabolism.

Excretion: Excreted in the urine as metabolites and unchanged drug (10-12%). Usual elimination half life of around 10-11 hr.

This medication is used short-term to treat symptoms of anxiety and nervousness. It acts on certain centers of the brain to help calm your nervous system.

How to use meprobamate

Take this medication by mouth with or without food, usually 2 to 4 times daily or as directed by your doctor.

Dosage is based on your age, medical condition, and response to treatment. Adults should not take more than 2400 milligrams in a 24-hour period.

Do not increase your dose or take this medication more often than prescribed. Your condition will not improve any faster, and the risk of serious side effects may be increased.

If this medication has been used regularly for a long time or in high doses, withdrawal symptoms (such as vomiting, shakiness, confusion, and rarely seizures) may occur if you suddenly stop using this medication. To prevent withdrawal reactions, your doctor may reduce your dose gradually. Consult your doctor or pharmacist for more details, and report any withdrawal reactions immediately.

When this medication is used for a long time, it may not work as well. Your doctor may need to increase your dose or change your medication. Talk with your doctor if this medication stops working well.

Along with its benefits, this medication may rarely cause abnormal drug-seeking behavior (addiction). This risk may be increased if you have abused alcohol or drugs in the past. Take this medication exactly as prescribed to lessen the risk of addiction.

Tell your doctor if your condition persists or worsens.

Drowsiness, dizziness, headache, excitement, nausea, vomiting, and diarrhea may occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly.

Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.

Tell your doctor immediately if any of these unlikely but serious side effects occur: numbness/tingling/swelling of arms/legs.

Tell your doctor immediately if any of these rare but very serious side effects occur: fast/irregular heartbeat, fainting, signs of infection (such as fever, persistent sore throat), easy bruising/bleeding, change in the amount of urine, unusual tiredness.

A very serious allergic reaction to this drug is rare. However, seek immediate medical attention if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.

This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.

Before taking meprobamate, tell your doctor or pharmacist if you are allergic to it; or to carisoprodol, mebutamate, tybamate, or carbromal; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: a certain liver/blood disorder (porphyria), kidney disease, liver disease, brain disorders (such as seizures, brain damage).

This drug may make you dizzy or drowsy. Do not drive, use machinery, or do any activity that requires alertness until you are sure you can perform such activities safely. Avoid alcoholic beverages.

Older adults may be more sensitive to the side effects of this drug, especially drowsiness and addiction. Drowsiness can increase the risk of falling.

This medication is not recommended for use during the first 3 months of pregnancy due to the potential for harm to an unborn baby. During the last 6 months of pregnancy, this medication should be used only when clearly needed. Discuss the risks and benefits with your doctor.

This medication passes into breast milk and may have undesirable effects on a nursing infant. Consult your doctor before breast-feeding.

 

Interactions:

The effects of some drugs can change if you take other drugs or herbal products at the same time. This can increase your risk for serious side effects or may cause your medications not to work correctly. These drug interactions are possible, but do not always occur. Your doctor or pharmacist can often prevent or manage interactions by changing how you use your medications or by close monitoring.

To help your doctor and pharmacist give you the best care, be sure to tell your doctor and pharmacist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products) before starting treatment with this product. While using this product, do not start, stop, or change the dosage of any other medicines you are using without your doctor’s approval.

Tell your doctor or pharmacist if you are taking other products that cause drowsiness, including alcohol, antihistamines (such as cetirizine, diphenhydramine), drugs for sleep or anxiety (such as alprazolam, diazepam, zolpidem), muscle relaxants (such as carisoprodol), and narcotic pain relievers (such as codeine).

Check the labels on all your medicines (such as allergy or cough-and-cold products) because they may contain ingredients that cause drowsiness. Ask your pharmacist about using those products safely.

This document does not contain all possible drug interactions. Keep a list of all the products you use. Share this list with your doctor and pharmacist to lessen your risk for serious medication problems.

If overdose is suspected, contact a poison control center or emergency room immediately.

Notes

Do not share this medication with others. It is against the law.

Keep all medical appointments. Your doctor will periodically monitor your progress or check for side effects. Consult your doctor for more details.

Missed Dose

If you are taking this on a regular schedule and you miss a dose, take it as soon as you remember. If it is near the time of the next dose, skip the missed dose and resume your usual dosing schedule. Do not double the dose to catch up.

Storage

Store at room temperature away from light and moisture. See packaging or consult your pharmacist for the exact temperature range. Do not store in the bathroom. Keep all medicines away from children and pets.

Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company for more details about how to safely discard your product.

 

Brands:

Available Brands:

Equanil

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