Manidipine is a drug that belongs to a class of medicines known as dihydropyridine calcium-channel blockers. This medicine blocks the entry of calcium in the muscle cells, thus leading to vasodilation.

Manidipine is used in the treatment of hypertension.

Manidipine should not be given to people with the following conditions:

  • Cardiogenic shock
  • Recent myocardial infarction
  • Acute unstable angina
  • Severe aortic stenosis

Manidipine may have the following side effects:

  • Dizziness
  • Flushing
  • Headache
  • Hypotension
  • Peripheral oedema
  • Tachycardia
  • Palpitations
  • Gastrointestinal disturbances
  • Increased urinary frequency
  • Lethargy
  • Eye pain
  • Depression
  • Ischaemic chest pain
  • Cerebral or myocardial ischaemia
  • Transient blindness
  • Rashes
  • Fever
  • Abnormal liver function
  • Gingival hyperplasia
  • Myalgia
  • Tremor
  • Impotence


Take extra caution in patients with the following conditions:

  • Hypotension
  • Poor cardiac reserve
  • Heart failure
  • Pregnancy
  • Lactation
  • Porphyria

Sudden withdrawal may exacerbate angina. Discontinue in patients who experience ischaemic pain following administration.



Manidipinemay interactwith the following medicines:

  • Aldesleukin
  • Antipsychotics
  • Insulin
  • Carbamazepine
  • Phenytoin
  • Rifampicin
  • Cimetidine
  • Erythromycin

If you think you may have overdosed on manidipine, seek medical help immediately.


Available Brands:

  • Caslot
  • Madipine
  • Manyper

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