Used as osmotic laxatives and bowel purgatives.

  • Should not be used in patients with the following conditions:
    • Intestinal perforation or obstruction, paralytic ileus; severe inflammatory conditions of the intestinal tract e.g. Crohn’s disease, ulcerative colitis and toxic megacolon; unexplained abdominal pain.
  • Caution for use in patients with Impaired gag reflex; reflux oesophagitis; DM; discontinue use if there is fluid and electrolyte imbalance;
  • If you are planning to be pregnant or think you may be pregnant, discuss the risks and benefits of use with your doctor.
  • Before breast-feeding, consult your physician.

Abdominal distension and pain; nausea, diarrhoea; anal irritation; allergic reactions e.g. rash, hives or swelling due to fluid retention.

Adult : By mouth

  • Bowel evacuation As macrogol 4,000 or 3,350 mixed w/ electrolytes: As solution containing about 59, 60 or 105 g/L of the macrogol: 200-300 mL repeated every 10-15 mins till the rectal effluent is clear. Max: 3-4 L.
  • Chronic constipation As solution containing 105 g/L of macrogol: 125 mL 1-3 times/day. Max duration: 2 wk.

Faecal impaction As solution containing 105 g/L of macrogol: 8 doses of 125 mL w/in 6 hr. Max duration: 3 days.

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